Specialty Building Blocks & Conjugation Chemistry
A chemistry-led partner for specialty building blocks, conjugation materials, and project-specific synthesis support.
CHEMOS is the custom chemistry and process development division of Chongqing Botao Biotechnology Co., Ltd. It focuses on specialty building blocks and scalable conjugation chemistry for oligonucleotide, peptide, ADC, PROTAC, radiopharmaceutical, and delivery applications.
The company operates two R&D bases in Chongqing and Weifang, Shandong, with more than 50 R&D professionals. The team specializes in route and process development and in transferring suitable processes from laboratory work to larger-scale production.
Three production bases are located in Chongqing, Hanzhong, Shaanxi, and Weifang, Shandong. The company works on more than 300 development projects each year, with scope, specifications, and production quantity confirmed for each project.
Our purpose is to make complex chemistry easier to evaluate and move forward. When a customer shares a target molecule or a route question, we help clarify what can be made, what needs to be checked, and what risks should be addressed before scale-up.
Quality starts with disciplined chemistry and transparent documentation. We support customers with practical route feedback, product information, technical communication, and batch-specific analytical data when available.
CHEMOS supplies high-barrier core molecules and project support for customers working with complex delivery-material, bioconjugation, radiopharmaceutical-precursor, protein-degradation, and specialty organic chemistry projects.
Ionizable and helper lipids, PEG-lipid derivatives, sterol components, GalNAc ligands, and functional handles used as inputs for nucleic-acid delivery research.
Cleavable and stable linker building blocks, spacers, click handles, and conjugation-ready intermediates for ADC and other conjugate workflows.
Non-radioactive DOTA, NOTA, DFO, and related bifunctional chelator building blocks and functionalized intermediates.
E3-ligase ligand derivatives, functionalized linkers, and bifunctional building blocks for PROTAC and proximity-inducing research.
Modified nucleosides, amino-acid derivatives, labeling reagents, and specialty scaffolds for defined synthetic routes.
Our work follows the way complex chemistry projects usually move in practice:
product fit, target structure, route feasibility, and starting-material discussion
reaction-condition work, impurity review, and process understanding
project-specific preparation when catalog material does not meet the structure, form, or quantity needed
feasible quantity, material handling, documentation, and delivery planning
method development, impurity confirmation, and batch-specific data review
The goal is to give customers a clear technical path before committing time and material to larger work.
CHEMOS works with demanding synthetic routes involving low-temperature chemistry, high-pressure reactions, sensitive reagents, and complex functional groups. Method choice is guided by target structure, impurity risk, safety considerations, and practical scale-up needs.
Our platform connects product and target review, route and process chemistry, analytical discussion, and project-specific supply planning. This helps customers understand feasibility, risk, documentation needs, and timing before committing to larger work.
We support technical evaluation and quality review with documented quality practices and batch-specific analytical data when required by the project.
