CHEMOS
DPPC

DPPC

Chemical Name

[(2R)-2,3-di(hexadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate

DPPC•LNP
Structure: DPPC structure, CAS 63-89-8, MW 734.04
Product No
CH51004
CAS
63-89-8
MF
C40H80NO8P
MW
734.04
Specification
Catalog No.CH51004
CAS No.63-89-8
Molecular FormulaC40H80NO8P
Molecular Weight734.04

CHEMOS Support for This Category

CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.

Overview

DPPC (also known as [(2R)-2,3-di(hexadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate) (CAS 63-89-8, MF C40H80NO8P, MW 734.04) is a phospholipid commonly used as a helper-lipid component in liposomal and LNP formulations. The chemistry conversation typically covers acyl-chain identity, head-group integrity, and related lysophospholipid species. Custom synthesis, process scale-up and supply planning are available through CHEMOS R&D and manufacturing facilities.

Applications

  • DPPC (CAS 63-89-8) preparation, route refinement, and analytical-control planning
  • Pulmonary surfactant and biophysical research applications
  • Process-development support for scalable phospholipid preparation
  • Helper phospholipid component in LNP and liposomal formulation research

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