CHEMOS
HSPC

HSPC

Chemical Name

(3-hexadecanoyloxy-2-octadecanoyloxypropyl) 2-(trimethylazaniumyl)ethyl phosphate

HSPC•LNP
Structure: HSPC structure, CAS 92128-87-5, MW 762.1
Product No
CH51006
CAS
92128-87-5
MF
C42H84NO8P
MW
762.1
Specification
Catalog No.CH51006
CAS No.92128-87-5
Molecular FormulaC42H84NO8P
Molecular Weight762.1

CHEMOS Support for This Category

CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.

Overview

HSPC (also known as (3-hexadecanoyloxy-2-octadecanoyloxypropyl) 2-(trimethylazaniumyl)ethyl phosphate) (CAS 92128-87-5, MF C42H84NO8P, MW 762.1) is a phospholipid commonly used as a helper-lipid component in liposomal and LNP formulations. The chemistry conversation typically covers acyl-chain identity, head-group integrity, and related lysophospholipid species. Project scale-up and custom synthesis are coordinated by the CHEMOS R&D team across laboratory and production sites.

Applications

  • HSPC (92128-87-5) as a starting point for downstream chemistry programs
  • Helper phospholipid component in LNP and liposomal formulation research
  • Bilayer-property studies in nucleic-acid delivery system development
  • Pulmonary surfactant and biophysical research applications

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