DSPE-PEG2000-NH2
DSPE-PEG2000-NH2
Product summary
Quick view
- Product family
- LNP & Nucleic Acid Delivery Lipids
- Chemical Name
- DSPE-PEG2000-NH2
- MF
- (C2H4O)nC43H84NO10P
DSPE-PEG2000-NH2 is an amine-terminated DSPE-PEG2000 PEG-lipid identified by CAS 474922-26-4.
This PEG2000 average-material entry is supported by ChemicalBook DSPE-PEG-NH2 / DSPE-PEG2000-NH2 naming with a PEG-distribution formula, while PubChem anchors the CAS to CID 156592378.
This catalog entry keeps to the PEG2000 identity, controlled synonyms, and published-research description for the material.
Identity and specifications
| Catalog No. | CH51012 |
| CAS No. | 474922-26-4 |
| Chemical Name | DSPE-PEG2000-NH2 |
| Synonyms | DSPE-PEG-NH2; DSPE-PEG2000-NH2; DSPE-PEG-2K-Amine; DSPE-PEG(2000) Amine |
| Material Representation | PEG2000 average-material PEG-lipid |
| Molecular Formula | (C2H4O)nC43H84NO10P |
| Average Molecular Weight | 2000 |
| PubChem CID | 156592378 |
Application context
- PEGylated liposome surface-grafting research: DSPE-PEG2000-NH2 has been reported in studies involving surface modification of PEGylated liposomes.
- Polymeric liposome and nanoparticle carrier research: the DSPE-PEG2000-NH2 name appears in literature on polymeric liposome and nanoparticle carrier systems.
- Functional PEG-lipid handle: the terminal amine provides a literature-described handle for PEG-lipid modification chemistry.
Additional material information
Characteristics
- DSPE phospholipid anchor connected to a PEG2000 chain.
- Terminal amine functionality for PEG-lipid modification chemistry.
- CAS 474922-26-4 is indexed by PubChem and ChemicalBook under DSPE-PEG-NH2 / DSPE-PEG2000-NH2 names.
Related technical resources
Public references
- DSPE-PEG 2000 Amine | PubChem CID 156592378
- High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing
PNAS, 2018
Product-family technical context
- Selective organ targeting nanoparticles for tissue-specific mRNA delivery and CRISPR-Cas gene editing
Nature Nanotechnology, 2020
Product-family technical context
- Rational Design of Cationic Lipids for siRNA Delivery
Nature Biotechnology, 2010
Product-family technical context
- Biodegradable Lipids Enabling Rapidly Eliminated Lipid Nanoparticles for Systemic Delivery of RNAi Therapeutics
Molecular Therapy, 2013
Product-family technical context
Frequently Asked Questions
Why does PubChem show a different molecular weight?
PubChem provides a fixed reference record for the CAS, while this catalog entry is a PEG2000 average-material PEG-lipid. The page therefore uses the PEG2000 average-material identity.
Which names are used for this product?
Common names include DSPE-PEG2000-NH2, DSPE-PEG-NH2, DSPE-PEG-2K-Amine, and DSPE-PEG(2000) Amine.
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