CHEMOS
DSPE

DSPE

Chemical Name

1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine

DSPE•LNP
Structure: DSPE structure, CAS 1069-79-0, MW 748.07
Product No
CH51013
CAS
1069-79-0
MF
C41H82NO8P
MW
748.07
Specification
Catalog No.CH51013
CAS No.1069-79-0
Molecular FormulaC41H82NO8P
Molecular Weight748.07

CHEMOS Support for This Category

CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.

Overview

DSPE (also known as 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine) (CAS 1069-79-0, MF C41H82NO8P, MW 748.07) belongs to the helper phospholipid class used in nucleic acid delivery system research and liposomal drug carriers. Typical chemistry topics include stereo-purity at the glycerol backbone, residual free fatty acid, and related diacyl regio-isomers. CHEMOS process chemistry, organic synthesis routes and project scale-up support are offered for downstream programs.

Applications

  • DSPE (CAS 1069-79-0) route review and custom analog preparation
  • Helper phospholipid component in LNP and liposomal formulation research
  • Bilayer-property studies in nucleic-acid delivery system development
  • Pulmonary surfactant and biophysical research applications

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