CHEMOS
DOPC

DOPC

Chemical Name

[(2R)-2,3-bis[[(Z)-octadec-9-enoyl]oxy]propyl] 2-(trimethylazaniumyl)ethyl phosphate

DOPC•LNP
Structure: DOPC structure, CAS 4235-95-4, MW 786.12
Product No
CH51019
CAS
4235-95-4
MF
C44H84NO8P
MW
786.12
Specification
Catalog No.CH51019
CAS No.4235-95-4
Molecular FormulaC44H84NO8P
Molecular Weight786.12

CHEMOS Support for This Category

CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.

Overview

DOPC (also known as [(2R)-2,3-bis[[(Z)-octadec-9-enoyl]oxy]propyl] 2-(trimethylazaniumyl)ethyl phosphate) (CAS 4235-95-4, MF C44H84NO8P, MW 786.12) is a phospholipid commonly used as a helper-lipid component in liposomal and LNP formulations. The chemistry conversation typically covers acyl-chain identity, head-group integrity, and related lysophospholipid species. Bench-scale to larger-scale production is supported through CHEMOS organic chemistry workflows and dedicated process-development resources.

Applications

  • DOPC (4235-95-4) supply and analog preparation for research programs
  • Pulmonary surfactant and biophysical research applications
  • Process-development support for scalable phospholipid preparation
  • Helper phospholipid component in LNP and liposomal formulation research

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