DSPE-PEG2000-Mal
Chemical Name
1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] ammonium
DSPE-PEG2000-Mal•LNP
Structure: 
Product No
CH51020
CAS
474922-22-0
MF
(C2H4O)nC51H92NO13P.H3N
MW
2000 (Average)
Specification
| Catalog No. | CH51020 |
| CAS No. | 474922-22-0 |
| Molecular Formula | (C2H4O)nC51H92NO13P.H3N |
| Molecular Weight | 2000 (Average) |
CHEMOS Support for This Category
CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.
Overview
DSPE-PEG2000-Mal (also known as 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] ammonium) (CAS 474922-22-0, MF (C2H4O)nC51H92NO13P.H3N, MW 2000 (Average)) belongs to the PEGylated lipid class used in LNP and liposome research. Programs typically discuss polydispersity of the PEG segment, lipid-anchor connectivity, and the terminal-group handle available for downstream conjugation. CHEMOS process chemistry, organic synthesis routes and project scale-up support are offered for downstream programs.
Applications
- DSPE-PEG2000-Mal (474922-22-0) supply and analog preparation for research programs
- Process-development support for scalable PEG-lipid preparation
- Analytical method development for PEG-lipid characterisation
- Stealth or functional PEG-lipid component in LNP / liposomal formulation research
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