Trioctanoin
Trioctanoin
Product summary
Quick view
- Product family
- LNP & Nucleic Acid Delivery Lipids
- Chemical Name
- Trioctanoin
- MF
- C27H50O6
- MW
- 470.7
Trioctanoin, also known as Tricaprylin, is a medium-chain triacylglycerol identified by CAS 538-23-8.
PubChem and ChemicalBook align this CAS with molecular formula C27H50O6, molecular weight about 470.7, and InChIKey VLPFTAMPNXLGLX-UHFFFAOYSA-N.
Although one catalog snapshot listed the name as Octanoic acid, CAS 538-23-8 identifies the triglyceride Trioctanoin / Tricaprylin rather than free octanoic acid.
Identity and specifications
| Catalog No. | CH51021 |
| CAS No. | 538-23-8 |
| Chemical Name | Trioctanoin |
| Synonyms | Tricaprylin; Glycerol tricaprylate; Glycerol trioctanoate; Glyceryl trioctanoate; Caprylic acid triglyceride; Octanoic acid triglyceride |
| Molecular Formula | C27H50O6 |
| Molecular Weight | 470.7 |
| PubChem CID | 10850 |
| IUPAC Name | 2,3-di(octanoyloxy)propyl octanoate |
| InChIKey | VLPFTAMPNXLGLX-UHFFFAOYSA-N |
Application context
- Lipid-based formulation research: tricaprylin has been reported in lipid-based formulation digestibility and lipolysis-rate studies.
- Triacylglycerol nanoparticle research: tricaprylin has been studied among medium-chain triacylglycerol nanoparticle systems.
- Liposphere formulation research: tricaprylin has been reported as a lipid-phase component in liposphere formulation studies.
Additional material information
Uses
Trioctanoin can be matched by CAS 538-23-8, formula C27H50O6, molecular weight about 470.7, PubChem CID 10850, and InChIKey VLPFTAMPNXLGLX-UHFFFAOYSA-N. For this catalog record, Trioctanoin / Tricaprylin is the corrected product identity.
Characteristics
- Glycerol triester bearing three octanoyl chains.
- Medium-chain triacylglycerol with formula C27H50O6 and molecular weight about 470.7.
- Indexed by PubChem and ChemicalBook under Trioctanoin / Tricaprylin for CAS 538-23-8.
Related technical resources
Public references
- Tricaprylin | PubChem CID 10850
- High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing
PNAS, 2018
Product-family technical context
- Selective organ targeting nanoparticles for tissue-specific mRNA delivery and CRISPR-Cas gene editing
Nature Nanotechnology, 2020
Product-family technical context
- Rational Design of Cationic Lipids for siRNA Delivery
Nature Biotechnology, 2010
Product-family technical context
- Biodegradable Lipids Enabling Rapidly Eliminated Lipid Nanoparticles for Systemic Delivery of RNAi Therapeutics
Molecular Therapy, 2013
Product-family technical context
Frequently Asked Questions
Is CAS 538-23-8 free Octanoic acid?
No. PubChem and ChemicalBook both map CAS 538-23-8 to Trioctanoin / Tricaprylin, the triglyceride, with formula C27H50O6.
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