CHEMOS
POPC

POPC

Chemical Name

1-Palmitoyl-2-oleoyl-sn-glycero-3-PC

POPC•LNP
Structure: POPC structure, CAS 26853-31-6, MW 760.08
Product No
CH51025
CAS
26853-31-6
MF
C42H82NO8P
MW
760.08
Specification
Catalog No.CH51025
CAS No.26853-31-6
Molecular FormulaC42H82NO8P
Molecular Weight760.08

CHEMOS Support for This Category

CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.

Overview

POPC (also known as 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC) (CAS 26853-31-6, MF C42H82NO8P, MW 760.08) is a helper-lipid phospholipid component of relevance to liposome and LNP research. Programs working with this lipid focus on chain-length specificity, oxidation control for unsaturated tails, and analytical separation of related species. Bench-scale to larger-scale production is supported through CHEMOS organic chemistry workflows and dedicated process-development resources.

Applications

  • POPC (26853-31-6) supply and analog preparation for research programs
  • Helper phospholipid component in LNP and liposomal formulation research
  • Pulmonary surfactant and biophysical research applications
  • Process-development support for scalable phospholipid preparation

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