DPPE
Chemical Name
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine
DPPE•LNP
Structure: 
Product No
CH51030
CAS
923-61-5
MF
C37H74NO8P
MW
691.97
Specification
| Catalog No. | CH51030 |
| CAS No. | 923-61-5 |
| Molecular Formula | C37H74NO8P |
| Molecular Weight | 691.97 |
CHEMOS Support for This Category
CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.
Overview
DPPE (also known as 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine) (CAS 923-61-5, MF C37H74NO8P, MW 691.97) is a phospholipid commonly used as a helper-lipid component in liposomal and LNP formulations. The chemistry conversation typically covers acyl-chain identity, head-group integrity, and related lysophospholipid species. Bench-scale to larger-scale production is supported through CHEMOS organic chemistry workflows and dedicated process-development resources.
Applications
- DPPE (CAS 923-61-5) route review and custom analog preparation
- Bilayer-property studies in nucleic-acid delivery system development
- Custom synthesis of acyl-chain or head-group variants
- Reference material in liposome composition optimisation studies
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