CHEMOS
DMPE

DMPE

Chemical Name

1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine

DMPE•LNP
Structure: DMPE structure, CAS 998-07-2, MW 635.85
Product No
CH51031
CAS
998-07-2
MF
C33H66NO8P
MW
635.85
Specification
Catalog No.CH51031
CAS No.998-07-2
Molecular FormulaC33H66NO8P
Molecular Weight635.85

CHEMOS Support for This Category

CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.

Overview

DMPE (also known as 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine) (CAS 998-07-2, MF C33H66NO8P, MW 635.85) belongs to the helper phospholipid class used in nucleic acid delivery system research and liposomal drug carriers. Typical chemistry topics include stereo-purity at the glycerol backbone, residual free fatty acid, and related diacyl regio-isomers. CHEMOS process-development team and large production base can support route refinement, scale-up and custom synthesis on request.

Applications

  • DMPE (998-07-2) supply and analog preparation for research programs
  • Pulmonary surfactant and biophysical research applications
  • Custom synthesis of acyl-chain or head-group variants
  • Process-development support for scalable phospholipid preparation

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