CHEMOS
Sodium cholesteryl sulfate

Sodium cholesteryl sulfate

Chemical Name

sodium [(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] sulfate

Sodium cholesteryl sulfate•LNP
Structure: Sodium cholesteryl sulfate structure, CAS 2864-50-8, MW 490.72
Product No
CH51036
CAS
2864-50-8
MF
C27H45NaO4S
MW
490.72
Specification
Catalog No.CH51036
CAS No.2864-50-8
Molecular FormulaC27H45NaO4S
Molecular Weight490.72

CHEMOS Support for This Category

CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.

Overview

Sodium cholesteryl sulfate (also known as sodium [(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] sulfate) (CAS 2864-50-8, MF C27H45NaO4S, MW 490.72) is used as an auxiliary lipid / sterol component in liposomal and LNP formulation research, often supporting bilayer stability or curvature control. Programs working with this material usually review identity, stereochemistry, and related sterol or surfactant species. Project scale-up and custom synthesis are coordinated by the CHEMOS R&D team across laboratory and production sites.

Applications

  • Sodium cholesteryl sulfate (CAS 2864-50-8) preparation, route refinement, and analytical-control planning
  • Sterol / surfactant supply for bilayer-property and curvature studies
  • Custom synthesis of related sterol or surfactant analogs
  • Process-development support for scalable auxiliary-lipid preparation

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