CHEMOS
O-LysoPE

O-LysoPE

Chemical Name

[(2R)-3-[2-aminoethoxy(hydroxy)phosphoryl]oxy-2-hydroxypropyl] (Z)-octadec-9-enoate

O-LysoPE•LNP
Structure: O-LysoPE structure, CAS 89576-29-4, MW 479.59
Product No
CH51038
CAS
89576-29-4
MF
C23H46NO7P
MW
479.59
Specification
Catalog No.CH51038
CAS No.89576-29-4
Molecular FormulaC23H46NO7P
Molecular Weight479.59

CHEMOS Support for This Category

CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.

Overview

O-LysoPE (also known as [(2R)-3-[2-aminoethoxy(hydroxy)phosphoryl]oxy-2-hydroxypropyl] (Z)-octadec-9-enoate) (CAS 89576-29-4, MF C23H46NO7P, MW 479.59) is a phospholipid commonly used as a helper-lipid component in liposomal and LNP formulations. The chemistry conversation typically covers acyl-chain identity, head-group integrity, and related lysophospholipid species. CHEMOS process-development team and large production base can support route refinement, scale-up and custom synthesis on request.

Applications

  • O-LysoPE (CAS 89576-29-4) preparation, route refinement, and analytical-control planning
  • Custom synthesis of acyl-chain or head-group variants
  • Process-development support for scalable phospholipid preparation
  • Reference material in liposome composition optimisation studies

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