DLin-KC2-DMA

DLin-KC2-DMA

Chemical Name

2-[2,2-bis[(9Z,12Z)-octadeca-9,12-dienyl]-1,3-dioxolan-4-yl]-N,N-dimethylethanamine

DLin-KC2-DMALNP
Structure: DLin-KC2-DMA structure, CAS 1190197-97-7, MW 642.09
Product No
CH51039
CAS
1190197-97-7
MF
C43H79NO2
MW
642.09
Specification
Catalog No.CH51039
CAS No.1190197-97-7
Molecular FormulaC43H79NO2
Molecular Weight642.09

CHEMOS Support for This Category

CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.

Overview

DLin-KC2-DMA (also known as 2-[2,2-bis[(9Z,12Z)-octadeca-9,12-dienyl]-1,3-dioxolan-4-yl]-N,N-dimethylethanamine) (CAS 1190197-97-7, MF C43H79NO2, MW 642.09) belongs to the ionizable lipid class used in LNP delivery system research for mRNA, siRNA and gene-editing cargos. Programs working with this compound usually examine the head-group / tail combination, related-substance profile, and stereochemistry. Bench-scale to larger-scale production is supported through CHEMOS organic chemistry workflows and dedicated process-development resources.

Applications

  • DLin-KC2-DMA (CAS 1190197-97-7) route review and custom analog preparation
  • Lipid nanoparticle (LNP) formulation research for mRNA / siRNA delivery
  • Ionizable lipid library and head-group / tail analog screening
  • Process-development support for scalable ionizable lipid preparation

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