CHEMOS
Lipid 5

Lipid 5

Chemical Name

nonyl 8-[(8-heptadecan-9-yloxy-8-oxooctyl)-(2-hydroxyethyl)amino]octanoate

Lipid 5•LNP
Structure: Lipid 5 structure, CAS 2089251-33-0, MW 710.17
Product No
CH51040
CAS
2089251-33-0
MF
C44H87NO5
MW
710.17
Specification
Catalog No.CH51040
CAS No.2089251-33-0
Molecular FormulaC44H87NO5
Molecular Weight710.17

CHEMOS Support for This Category

CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.

Overview

Lipid 5 (also known as nonyl 8-[(8-heptadecan-9-yloxy-8-oxooctyl)-(2-hydroxyethyl)amino]octanoate) (CAS 2089251-33-0, MF C44H87NO5, MW 710.17) belongs to the ionizable lipid class used in LNP delivery system research for mRNA, siRNA and gene-editing cargos. Programs working with this compound usually examine the head-group / tail combination, related-substance profile, and stereochemistry. CHEMOS process chemistry, organic synthesis routes and project scale-up support are offered for downstream programs.

Applications

  • Lipid 5 (CAS 2089251-33-0) route review and custom analog preparation
  • Custom analog synthesis with controlled head-group and tail variants
  • Analytical method development for ionizable lipid related substances
  • Ionizable lipid library and head-group / tail analog screening

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