DSPE-PEG2000-COOH
DSPE-PEG2000-COOH
Product summary
Quick view
- Product family
- LNP & Nucleic Acid Delivery Lipids
- Chemical Name
- DSPE-PEG2000-COOH
- MF
- (C2H4O)nC44H84NO12P.H3N
DSPE-PEG2000-COOH is a carboxyl-terminated DSPE-PEG material identified by CAS 474922-20-8.
ChemicalBook lists this CAS record with the PEG-average formula representation (C2H4O)nC44H84NO12P.H3N.
This catalog entry presents DSPE-PEG2000-COOH as a carboxylated PEG-lipid reference for PEGylated liposome and amine-coupling research studies.
Identity and specifications
| Catalog No. | CH51054 |
| CAS No. | 474922-20-8 |
| Chemical Name | DSPE-PEG2000-COOH |
| Synonyms | DSPE-PEG-2K-CH2COOH; DSPE-PEG(2000) Carboxylic Acid; DSPE-PEG-COOH; 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000] ammonium salt |
| Molecular Formula | (C2H4O)nC44H84NO12P.H3N |
| Molecular Weight | PEG2000 average material; no single fixed MW value is assigned in the public source records |
| Reference Source For Formula | ChemicalBook CAS-anchored PEG-average representation |
Application context
- DSPE-PEG2000-COOH identity work: supports matching DSPE-PEG2000-COOH, DSPE-PEG-2K-CH2COOH, and DSPE-PEG(2000) Carboxylic Acid naming to CAS 474922-20-8.
- Carboxylated PEG-lipid research: provides a reference point for DSPE-PEG materials bearing a carboxyl-terminated PEG chain.
- PEGylated liposome studies: DSPE-PEG-COOH terms are reported in literature involving PEGylated liposome and nanoliposome research systems.
Additional material information
Uses
DSPE-PEG2000-COOH can be matched by CAS 474922-20-8 and ChemicalBook naming for DSPE-PEG(2000) Carboxylic Acid. The page is focused on carboxylated DSPE-PEG identity, synonym control, and PEG-lipid research.
Characteristics
- Carboxyl-terminated DSPE-PEG material represented by DSPE-PEG2000-COOH naming.
- Formula is expressed as (C2H4O)nC44H84NO12P.H3N to reflect the ChemicalBook CAS-anchored PEG-average representation.
- Combines a DSPE lipid portion with a PEG2000 carboxyl-chain representation.
Related technical resources
Public references
- CID 156591922 | PubChem CID 156591922
- High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing
PNAS, 2018
Product-family technical context
- Selective organ targeting nanoparticles for tissue-specific mRNA delivery and CRISPR-Cas gene editing
Nature Nanotechnology, 2020
Product-family technical context
- Rational Design of Cationic Lipids for siRNA Delivery
Nature Biotechnology, 2010
Product-family technical context
- Biodegradable Lipids Enabling Rapidly Eliminated Lipid Nanoparticles for Systemic Delivery of RNAi Therapeutics
Molecular Therapy, 2013
Product-family technical context
Frequently Asked Questions
Which formula is used?
The page uses the current ChemicalBook CAS-anchored PEG-average formula representation: (C2H4O)nC44H84NO12P.H3N.
Why is there no fixed molecular weight?
DSPE-PEG2000-COOH is treated as a PEG-average material in the current record, so fixed PubChem reference MW values are not used as the product specification.
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