CHEMOS
DSPE-PEG2000-COOH

DSPE-PEG2000-COOH

DSPE-PEG2000-COOH•LNP
Structure: DSPE-PEG2000-COOH structure, CAS 474922-20-8, MW 2000 (Average)
Product No
CH51054
CAS
474922-20-8
MF
(C2H4O)nC46H88NO13P
MW
2000 (Average)
Specification
Catalog No.CH51054
CAS No.474922-20-8
Molecular Formula(C2H4O)nC46H88NO13P
Molecular Weight2000 (Average)

CHEMOS Support for This Category

CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.

Overview

DSPE-PEG2000-COOH (CAS 474922-20-8, MF (C2H4O)nC46H88NO13P, MW 2000 (Average)) is a PEG-lipid conjugate used as a stealth or functional component in nucleic-acid delivery systems. Practical chemistry questions involve PEG repeat distribution, lipid anchor integrity, and terminal-group functionalisation strategy. CHEMOS process-development team and large production base can support route refinement, scale-up and custom synthesis on request.

Applications

  • DSPE-PEG2000-COOH (CAS 474922-20-8) preparation, route refinement, and analytical-control planning
  • PEG length and lipid-anchor variation studies for nucleic-acid delivery
  • Custom synthesis of PEG-lipid analogs with controlled molecular weight
  • Analytical method development for PEG-lipid characterisation

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