1-Palmitoyl-sn-glycero-3-phosphoethanolamine
Chemical Name
[(2R)-3-[2-aminoethoxy(hydroxy)phosphoryl]oxy-2-hydroxypropyl] hexadecanoate
1-Palmitoyl-sn-glycero-3-phosphoethanolamine•LNP
Structure: 
Product No
CH51055
CAS
53862-35-4
MF
C21H44NO7P
MW
453.55
Specification
| Catalog No. | CH51055 |
| CAS No. | 53862-35-4 |
| Molecular Formula | C21H44NO7P |
| Molecular Weight | 453.55 |
CHEMOS Support for This Category
CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.
Overview
1-Palmitoyl-sn-glycero-3-phosphoethanolamine (also known as [(2R)-3-[2-aminoethoxy(hydroxy)phosphoryl]oxy-2-hydroxypropyl] hexadecanoate) (CAS 53862-35-4, MF C21H44NO7P, MW 453.55) belongs to the helper phospholipid class used in nucleic acid delivery system research and liposomal drug carriers. Typical chemistry topics include stereo-purity at the glycerol backbone, residual free fatty acid, and related diacyl regio-isomers. Bench-scale to larger-scale production is supported through CHEMOS organic chemistry workflows and dedicated process-development resources.
Applications
- 1-Palmitoyl-sn-glycero-3-phosphoethanolamine (CAS 53862-35-4) route review and custom analog preparation
- Helper phospholipid component in LNP and liposomal formulation research
- Bilayer-property studies in nucleic-acid delivery system development
- Pulmonary surfactant and biophysical research applications
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