1,2-Di-DHA-sn-glycero-3-phosphocholine
1,2-Di-DHA-sn-glycero-3-phosphocholine

Product summary
Quick view
- Product family
- LNP & Nucleic Acid Delivery Lipids
- Chemical Name
- 1,2-Di-DHA-sn-glycero-3-phosphocholine
- MF
- C52H80NO8P
- MW
- 878.17
1,2-Di-DHA-sn-glycero-3-phosphocholine is an all-cis didocosahexaenoyl phosphatidylcholine identified by CAS 99296-81-8.
PubChem and ChemicalBook support the formula C52H80NO8P, and ChemicalBook lists molecular weight 878.17.
The page presents this lipid as PC(22:6/22:6), with research in omega-3 lipid bilayers, membrane interaction studies, monolayers, and polyunsaturated phospholipid oxidation.
Identity and specifications
| Catalog No. | CH51060 |
| CAS No. | 99296-81-8 |
| Chemical Name | 1,2-Di-DHA-sn-glycero-3-phosphocholine |
| Synonyms | PC(22:6/22:6); DHAPC; 22:6 PC (cis); 1,2-didocosahexaenoyl-sn-glycero-3-phosphocholine |
| Molecular Formula | C52H80NO8P |
| Molecular Weight | 878.17 |
| Reference Source For Formula/MW | PubChem / ChemicalBook all-cis representation |
Application context
- Di-DHA phosphatidylcholine identity work: supports matching 1,2-Di-DHA-sn-glycero-3-phosphocholine, PC(22:6/22:6), DHAPC, and 22:6 PC naming to CAS 99296-81-8.
- Omega-3 lipid bilayer research: didocosahexaenoyl phosphatidylcholine terms appear in literature involving omega-3-containing lipid bilayers and membrane interaction studies.
- Polyunsaturated phospholipid studies: related literature covers oxidation and monolayer behavior of polyunsaturated phospholipid systems.
Additional material information
Uses
1,2-Di-DHA-sn-glycero-3-phosphocholine can be matched by CAS 99296-81-8 and public all-cis PC(22:6/22:6) records. The page is focused on identity, synonym control, and polyunsaturated phosphatidylcholine research.
Characteristics
- All-cis didocosahexaenoyl phosphatidylcholine represented by PC(22:6/22:6) and DHAPC naming.
- Formula C52H80NO8P follows PubChem and ChemicalBook; molecular weight 878.17 follows ChemicalBook.
- Polyunsaturated phosphatidylcholine with two DHA-chain representations.
Related technical resources
Public references
- 1,2-Docosahexanoyl-sn-glycero-3-phosphocholine | PubChem CID 24779134
- High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing
PNAS, 2018
Product-family technical context
- Selective organ targeting nanoparticles for tissue-specific mRNA delivery and CRISPR-Cas gene editing
Nature Nanotechnology, 2020
Product-family technical context
- Rational Design of Cationic Lipids for siRNA Delivery
Nature Biotechnology, 2010
Product-family technical context
- Biodegradable Lipids Enabling Rapidly Eliminated Lipid Nanoparticles for Systemic Delivery of RNAi Therapeutics
Molecular Therapy, 2013
Product-family technical context
Frequently Asked Questions
Which names are relevant for this product?
Relevant names include PC(22:6/22:6), DHAPC, 22:6 PC, and 1,2-didocosahexaenoyl-sn-glycero-3-phosphocholine.
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