CHEMOS
Hexane-1,6-diol

Hexane-1,6-diol

Hexane-1,6-diol•PROTAC
Structure: Hexane-1,6-diol structure, CAS 629-11-8, MW 118.17
Product No
CH56005
CAS
629-11-8
MF
C6H14O2
MW
118.17
Specification
Catalog No.CH56005
CAS No.629-11-8
Molecular FormulaC6H14O2
Molecular Weight118.17

CHEMOS Support for This Category

CHEMOS supports PROTAC building-block projects covering linkers, E3 ligase recruiter derivatives, and customized degrader intermediates. Linker building blocks : PEG acids, PEG azides, alkyl spacers, branched linkers, and rigid linkers. E3 recruiter derivatives : IMiD-related, VHL-related, and other recruiter building blocks for medicinal chemistry programs. Custom synthesis : linker design, functional-group installation, and intermediate preparation. Route and purification review : multi-step synthesis planning with attention to polarity, solubility, and impurity control. Scale-up evaluation : larger-batch preparation can be assessed after route feasibility review.

Overview

Hexane-1,6-diol (CAS 629-11-8, MF C6H14O2, MW 118.17) is used as a PROTAC research building block in degrader chemistry. Typical chemistry questions involve route design for the bifunctional architecture, linker selection, and analytical control of residual reagents. CHEMOS process-development team and large production base can support route refinement, scale-up and custom synthesis on request.

Applications

  • Hexane-1,6-diol (CAS 629-11-8) preparation, route refinement, and analytical-control planning
  • PROTAC building block — linker / E3-ligand / degrader handle
  • Bifunctional degrader synthesis with orthogonal protecting groups
  • Linker-length and composition exploration for degrader optimisation

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Our CDMO team provides end-to-end custom synthesis support from discovery through process development and scale-up.

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