CHEMOS
Bis(2-bromoethyl) ether

Bis(2-bromoethyl) ether

Chemical Name

1-bromo-2-(2-bromoethoxy)ethane

Bis(2-bromoethyl) ether•PROTAC
Structure: Bis(2-bromoethyl) ether structure, CAS 5414-19-7, MW 231.91
Product No
CH56002
CAS
5414-19-7
MF
C4H8Br2O
MW
231.91
Specification
Catalog No.CH56002
CAS No.5414-19-7
Molecular FormulaC4H8Br2O
Molecular Weight231.91

CHEMOS Support for This Category

CHEMOS supports PROTAC building-block projects covering linkers, E3 ligase recruiter derivatives, and customized degrader intermediates. Linker building blocks : PEG acids, PEG azides, alkyl spacers, branched linkers, and rigid linkers. E3 recruiter derivatives : IMiD-related, VHL-related, and other recruiter building blocks for medicinal chemistry programs. Custom synthesis : linker design, functional-group installation, and intermediate preparation. Route and purification review : multi-step synthesis planning with attention to polarity, solubility, and impurity control. Scale-up evaluation : larger-batch preparation can be assessed after route feasibility review.

Overview

Bis(2-bromoethyl) ether (also known as 1-bromo-2-(2-bromoethoxy)ethane) (CAS 5414-19-7, MF C4H8Br2O, MW 231.91) is a PROTAC research building block — typically a linker, E3-ligase ligand, or degrader handle. Practical chemistry topics include orthogonal protecting groups, modular linker chemistry, and stereo-purity at chiral centres. Bench-scale to larger-scale production is supported through CHEMOS organic chemistry workflows and dedicated process-development resources.

Applications

  • Bis(2-bromoethyl) ether (CAS 5414-19-7) route review and custom analog preparation
  • Reference material in targeted protein degradation chemistry programs
  • PROTAC building block — linker / E3-ligand / degrader handle
  • Bifunctional degrader synthesis with orthogonal protecting groups

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