NH2-PEG4-CH2CH2COOH
Chemical Name
3-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]propanoic acid
NH2-PEG4-CH2CH2COOH•PROTAC
Structure: 
Product No
CH56010
CAS
663921-15-1
MF
C11H23NO6
MW
265.3
Specification
| Catalog No. | CH56010 |
| CAS No. | 663921-15-1 |
| Molecular Formula | C11H23NO6 |
| Molecular Weight | 265.3 |
CHEMOS Support for This Category
CHEMOS supports PROTAC building-block projects covering linkers, E3 ligase recruiter derivatives, and customized degrader intermediates. Linker building blocks : PEG acids, PEG azides, alkyl spacers, branched linkers, and rigid linkers. E3 recruiter derivatives : IMiD-related, VHL-related, and other recruiter building blocks for medicinal chemistry programs. Custom synthesis : linker design, functional-group installation, and intermediate preparation. Route and purification review : multi-step synthesis planning with attention to polarity, solubility, and impurity control. Scale-up evaluation : larger-batch preparation can be assessed after route feasibility review.
Overview
NH2-PEG4-CH2CH2COOH (also known as 3-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]propanoic acid) (CAS 663921-15-1, MF C11H23NO6, MW 265.3) is used as a PROTAC research building block in degrader chemistry. Typical chemistry questions involve route design for the bifunctional architecture, linker selection, and analytical control of residual reagents. CHEMOS process-development team and large production base can support route refinement, scale-up and custom synthesis on request.
Applications
- NH2-PEG4-CH2CH2COOH (CAS 663921-15-1) route review and custom analog preparation
- Process-development support for scalable building-block preparation
- Reference material in targeted protein degradation chemistry programs
- PROTAC building block — linker / E3-ligand / degrader handle
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