CHEMOS
Fmoc-NH-PEG4-CH2CH2COOH

Fmoc-NH-PEG4-CH2CH2COOH

Chemical Name

3-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid

Fmoc-NH-PEG4-CH2CH2COOH•PROTAC
Structure: Fmoc-NH-PEG4-CH2CH2COOH structure, CAS 557756-85-1, MW 487.54
Product No
CH56015
CAS
557756-85-1
MF
C26H33NO8
MW
487.54
Specification
Catalog No.CH56015
CAS No.557756-85-1
Molecular FormulaC26H33NO8
Molecular Weight487.54

CHEMOS Support for This Category

CHEMOS supports PROTAC building-block projects covering linkers, E3 ligase recruiter derivatives, and customized degrader intermediates. Linker building blocks : PEG acids, PEG azides, alkyl spacers, branched linkers, and rigid linkers. E3 recruiter derivatives : IMiD-related, VHL-related, and other recruiter building blocks for medicinal chemistry programs. Custom synthesis : linker design, functional-group installation, and intermediate preparation. Route and purification review : multi-step synthesis planning with attention to polarity, solubility, and impurity control. Scale-up evaluation : larger-batch preparation can be assessed after route feasibility review.

Overview

Fmoc-NH-PEG4-CH2CH2COOH (also known as 3-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid) (CAS 557756-85-1, MF C26H33NO8, MW 487.54) belongs to the PROTAC building-block class (linker / E3 ligand / warhead). Programs working with this compound typically focus on coupling-handle compatibility, linker length / composition exploration, and impurity control. CHEMOS process-development team and large production base can support route refinement, scale-up and custom synthesis on request.

Applications

  • Fmoc-NH-PEG4-CH2CH2COOH (557756-85-1) as a starting point for downstream chemistry programs
  • Custom analog synthesis with controlled coupling handles
  • Process-development support for scalable building-block preparation
  • Reference material in targeted protein degradation chemistry programs

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