5-Hexynoic acid
5-Hexynoic acid

Product summary
Quick view
- Product family
- PROTAC, E3 Ligands & Proximity-Inducing Building Blocks
- Chemical Name
- 5-Hexynoic acid
- MF
- C6H8O2
- MW
- 112.13
5-Hexynoic acid is the product name for catalog CH56019.
This record matches CAS 53293-00-8, molecular formula C6H8O2, molecular weight 112.13, and PubChem CID 143036.
The IUPAC name hex-5-ynoic acid refers to the same compound identity.
Identity and specifications
| Catalog No. | CH56019 |
| CAS No. | 53293-00-8 |
| Chemical Name | 5-Hexynoic acid |
| IUPAC Name | hex-5-ynoic acid |
| Molecular Formula | C6H8O2 |
| Molecular Weight | 112.13 |
| PubChem CID | 143036 |
Related technical resources
PROTAC / TPD Building Blocks
CRBN and VHL ligand derivatives, ligand-linkers, bifunctional degrader intermediates, and linker-tuning building blocks.
PROTAC Linker Selection
Build linker series from both ligands, exit vectors, ternary-complex geometry, conformation, permeability, synthesis, and assay evidence.
Public references
- 5-Hexynoic acid | PubChem CID 143036
- Catalytic in vivo protein knockdown by small-molecule PROTACs
Nature Chemical Biology, 2015
Product-family technical context
- Structural basis of PROTAC cooperative recognition for selective protein degradation
Nature Chemical Biology, 2017
Product-family technical context
- Structural Basis of PROTAC Cooperative Recognition for Selective Protein Degradation
Nature Chemical Biology, 2017
Product-family technical context
- Direct-to-Biology Accelerates PROTAC Synthesis and the Evaluation of Linker Effects on Permeability and Degradation
ACS Medicinal Chemistry Letters, 2022
Product-family technical context
Frequently Asked Questions
What is 5-Hexynoic acid?
CH56019 is 5-Hexynoic acid, CAS 53293-00-8, with molecular formula C6H8O2, molecular weight 112.13, and PubChem CID 143036.
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