CHEMOS
1-(4-Bromo-2-chlorophenyl)dihydropyrimidine-2,4(1H,3H)-dione

1-(4-Bromo-2-chlorophenyl)dihydropyrimidine-2,4(1H,3H)-dione

Chemical Name

1-(4-bromo-2-chlorophenyl)-1,3-diazinane-2,4-dione

1-(4-Bromo-2-chlorophenyl)dihydropyrimidine-2,4(1H,3H)-dione•Molecular Glues
Structure: 1-(4-Bromo-2-chlorophenyl)dihydropyrimidine-2,4(1H,3H)-dione structure, CAS 1517523-15-7, MW 303.54
Product No
CH57001
CAS
1517523-15-7
MF
C10H8BrClN2O2
MW
303.54
Specification
Catalog No.CH57001
CAS No.1517523-15-7
Molecular FormulaC10H8BrClN2O2
Molecular Weight303.54

CHEMOS Support for This Category

CHEMOS supports molecular glue and small-molecule degrader building-block chemistry, including analog preparation and route optimization. Scaffold preparation : IMiD-related analogs, sulfonamide motifs, and other functionalized small-molecule scaffolds. Custom analog synthesis : substituent variation, linker-ready handles, and SAR-oriented intermediate preparation. Chiral and stereochemical review : chiral separation or asymmetric synthesis can be evaluated where relevant. Analytical support : HPLC, NMR, MS, and purity-method development according to project needs. Process development : route refinement and scale-up planning after technical review.

Overview

1-(4-Bromo-2-chlorophenyl)dihydropyrimidine-2,4(1H,3H)-dione (also known as 1-(4-bromo-2-chlorophenyl)-1,3-diazinane-2,4-dione) (CAS 1517523-15-7, MF C10H8BrClN2O2, MW 303.54) is studied as a molecular glue / E3-ligase research scaffold for targeted protein degradation. Practical chemistry questions involve route consistency, chiral integrity, and analytical control of related impurities. CHEMOS process-development team and large production base can support route refinement, scale-up and custom synthesis on request.

Applications

  • 1-(4-Bromo-2-chlorophenyl)dihydropyrimidine-2,4(1H,3H)-dione (CAS 1517523-15-7) route review and custom analog preparation
  • Process-development support for scalable scaffold preparation
  • Reference research scaffold in degrader chemistry programs
  • Molecular glue research scaffold for targeted protein degradation

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