Lenalidomide

Lenalidomide

Chemical Name

3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione

LenalidomideMolecular Glues
Structure: Lenalidomide structure, CAS 191732-72-6, MW 259.26
Product No
CH57002
CAS
191732-72-6
MF
C13H13N3O3
MW
259.26
Specification
Catalog No.CH57002
CAS No.191732-72-6
Molecular FormulaC13H13N3O3
Molecular Weight259.26

CHEMOS Support for This Category

CHEMOS supports molecular glue and small-molecule degrader building-block chemistry, including analog preparation and route optimization. Scaffold preparation : IMiD-related analogs, sulfonamide motifs, and other functionalized small-molecule scaffolds. Custom analog synthesis : substituent variation, linker-ready handles, and SAR-oriented intermediate preparation. Chiral and stereochemical review : chiral separation or asymmetric synthesis can be evaluated where relevant. Analytical support : HPLC, NMR, MS, and purity-method development according to project needs. Process development : route refinement and scale-up planning after technical review.

Overview

Lenalidomide (also known as 3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione) (CAS 191732-72-6, MF C13H13N3O3, MW 259.26) is studied as a molecular glue / E3-ligase research scaffold for targeted protein degradation. Practical chemistry questions involve route consistency, chiral integrity, and analytical control of related impurities. CHEMOS process chemistry, organic synthesis routes and project scale-up support are offered for downstream programs.

Applications

  • Lenalidomide (191732-72-6) supply and analog preparation for research programs
  • Process-development support for scalable scaffold preparation
  • Molecular glue research scaffold for targeted protein degradation
  • Custom synthesis of analog series for SAR exploration

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