Lenalidomide
Lenalidomide
Product summary
Quick view
- Product family
- PROTAC, E3 Ligands & Proximity-Inducing Building Blocks
- Chemical Name
- Lenalidomide
- MF
- C13H13N3O3
- MW
- 259.26
Lenalidomide is an IMiD compound identified by CAS 191732-72-6.
The verified record matches molecular formula C13H13N3O3, molecular weight 259.26, PubChem CID 216326, and InChIKey GOTYRUGSSMKFNF-UHFFFAOYSA-N.
Lenalidomide is reported in cereblon/IMiD and molecular-glue research literature; the identifiers below keep that research tied to the confirmed compound identity.
Identity and specifications
| Catalog No. | CH57002 |
| CAS No. | 191732-72-6 |
| Chemical Name | Lenalidomide |
| Molecular Formula | C13H13N3O3 |
| Molecular Weight | 259.26 |
| PubChem CID | 216326 |
| IUPAC Name | 3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione |
| InChIKey | GOTYRUGSSMKFNF-UHFFFAOYSA-N |
Application context
- Cereblon/IMiD research: Lenalidomide is frequently referenced in literature discussing cereblon-associated IMiD chemistry.
- Molecular-glue research background: PubMed records connect Lenalidomide with molecular-glue research language in the published literature.
- Identity and catalog alignment: supports matching CAS 191732-72-6, formula C13H13N3O3, PubChem CID 216326, and InChIKey GOTYRUGSSMKFNF-UHFFFAOYSA-N.
Additional material information
Characteristics
- IMiD compound with an isoindolinone-linked glutarimide framework.
- Formula C13H13N3O3 and molecular weight 259.26 align between CHEMOS source data and PubChem.
- CAS and exact-name lookups both resolve to PubChem CID 216326.
Related technical resources
PROTAC / TPD Building Blocks
CRBN and VHL ligand derivatives, ligand-linkers, bifunctional degrader intermediates, and linker-tuning building blocks.
PROTAC Linker Selection
Build linker series from both ligands, exit vectors, ternary-complex geometry, conformation, permeability, synthesis, and assay evidence.
Public references
- Lenalidomide | PubChem CID 216326
- Catalytic in vivo protein knockdown by small-molecule PROTACs
Nature Chemical Biology, 2015
Product-family technical context
- Structural basis of PROTAC cooperative recognition for selective protein degradation
Nature Chemical Biology, 2017
Product-family technical context
- Structural Basis of PROTAC Cooperative Recognition for Selective Protein Degradation
Nature Chemical Biology, 2017
Product-family technical context
- Direct-to-Biology Accelerates PROTAC Synthesis and the Evaluation of Linker Effects on Permeability and Degradation
ACS Medicinal Chemistry Letters, 2022
Product-family technical context
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