Tasisulam
Tasisulam
Product summary
Quick view
- Product family
- PROTAC, E3 Ligands & Proximity-Inducing Building Blocks
- Chemical Name
- Tasisulam
- MF
- C11H6BrCl2NO3S2
- MW
- 415.1
Tasisulam is a sulfonyl benzamide compound identified by CAS 519055-62-0.
The verified record matches molecular formula C11H6BrCl2NO3S2, molecular weight about 415.1, PubChem CID 10160238, and InChIKey WWONFUQGBVOKOF-UHFFFAOYSA-N.
Published records place Tasisulam in RBM39/DCAF15 and molecular-glue research discussions; the identifiers below anchor that context to the confirmed compound identity.
Identity and specifications
| Catalog No. | CH57003 |
| CAS No. | 519055-62-0 |
| Chemical Name | Tasisulam |
| Molecular Formula | C11H6BrCl2NO3S2 |
| Molecular Weight | 415.1 |
| PubChem CID | 10160238 |
| IUPAC Name | N-(5-bromothiophen-2-yl)sulfonyl-2,4-dichlorobenzamide |
| InChIKey | WWONFUQGBVOKOF-UHFFFAOYSA-N |
Application context
- RBM39/DCAF15 research: Tasisulam appears in published literature discussing RBM39/DCAF15-associated molecular-glue research.
- Sulfonyl benzamide identity reference: supports comparison of the bromothiophene sulfonyl and dichlorobenzamide structural features.
- Catalog data alignment: helps keep CAS 519055-62-0, formula C11H6BrCl2NO3S2, PubChem CID 10160238, and InChIKey WWONFUQGBVOKOF-UHFFFAOYSA-N consistent across records.
Additional material information
Characteristics
- Sulfonyl benzamide structure containing a bromothiophene group and a dichlorobenzamide unit.
- Halogenated sulfur-containing compound with formula C11H6BrCl2NO3S2.
- CAS and exact-name lookups both resolve to PubChem CID 10160238.
Related technical resources
PROTAC / TPD Building Blocks
CRBN and VHL ligand derivatives, ligand-linkers, bifunctional degrader intermediates, and linker-tuning building blocks.
PROTAC Linker Selection
Build linker series from both ligands, exit vectors, ternary-complex geometry, conformation, permeability, synthesis, and assay evidence.
Public references
- Tasisulam | PubChem CID 10160238
- Catalytic in vivo protein knockdown by small-molecule PROTACs
Nature Chemical Biology, 2015
Product-family technical context
- Structural basis of PROTAC cooperative recognition for selective protein degradation
Nature Chemical Biology, 2017
Product-family technical context
- Structural Basis of PROTAC Cooperative Recognition for Selective Protein Degradation
Nature Chemical Biology, 2017
Product-family technical context
- Direct-to-Biology Accelerates PROTAC Synthesis and the Evaluation of Linker Effects on Permeability and Degradation
ACS Medicinal Chemistry Letters, 2022
Product-family technical context
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