Indisulam
Indisulam
Product summary
Quick view
- Product family
- PROTAC, E3 Ligands & Proximity-Inducing Building Blocks
- Chemical Name
- Indisulam
- MF
- C14H12ClN3O4S2
- MW
- 385.8
Indisulam is an indole-linked sulfonamide compound identified by CAS 165668-41-7.
The verified record matches molecular formula C14H12ClN3O4S2, molecular weight about 385.8, PubChem CID 216468, and InChIKey SETFNECMODOHTO-UHFFFAOYSA-N.
Published records place Indisulam in RBM39/DCAF15 and molecular-glue research discussions; the identifiers below keep that context attached to the confirmed compound identity.
Identity and specifications
| Catalog No. | CH57004 |
| CAS No. | 165668-41-7 |
| Chemical Name | Indisulam |
| Molecular Formula | C14H12ClN3O4S2 |
| Molecular Weight | 385.8 |
| PubChem CID | 216468 |
| IUPAC Name | 4-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide |
| InChIKey | SETFNECMODOHTO-UHFFFAOYSA-N |
Application context
- RBM39/DCAF15 research: Indisulam appears in published literature discussing RBM39/DCAF15-associated molecular-glue research.
- Indole sulfonamide identity reference: supports comparison of the chloroindole and benzenedisulfonamide structural features.
- Catalog data alignment: helps keep CAS 165668-41-7, formula C14H12ClN3O4S2, PubChem CID 216468, and InChIKey SETFNECMODOHTO-UHFFFAOYSA-N consistent across records.
Additional material information
Characteristics
- Indole-linked disulfonamide structure containing a chloroindole group.
- Sulfur-containing heteroaromatic compound with formula C14H12ClN3O4S2.
- CAS and exact-name lookups both resolve to PubChem CID 216468.
Related technical resources
PROTAC / TPD Building Blocks
CRBN and VHL ligand derivatives, ligand-linkers, bifunctional degrader intermediates, and linker-tuning building blocks.
PROTAC Linker Selection
Build linker series from both ligands, exit vectors, ternary-complex geometry, conformation, permeability, synthesis, and assay evidence.
Public references
- Indisulam | PubChem CID 216468
- Catalytic in vivo protein knockdown by small-molecule PROTACs
Nature Chemical Biology, 2015
Product-family technical context
- Structural basis of PROTAC cooperative recognition for selective protein degradation
Nature Chemical Biology, 2017
Product-family technical context
- Structural Basis of PROTAC Cooperative Recognition for Selective Protein Degradation
Nature Chemical Biology, 2017
Product-family technical context
- Direct-to-Biology Accelerates PROTAC Synthesis and the Evaluation of Linker Effects on Permeability and Degradation
ACS Medicinal Chemistry Letters, 2022
Product-family technical context
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