NRX-1933
Chemical Name
2-oxo-N-[3-(2H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)-1H-pyridine-3-carboxamide
NRX-1933•Molecular Glues
Structure: 
Product No
CH57012
CAS
2763260-30-4
MF
C14H9F3N6O2
MW
350.26
Specification
| Catalog No. | CH57012 |
| CAS No. | 2763260-30-4 |
| Molecular Formula | C14H9F3N6O2 |
| Molecular Weight | 350.26 |
CHEMOS Support for This Category
CHEMOS supports molecular glue and small-molecule degrader building-block chemistry, including analog preparation and route optimization. Scaffold preparation : IMiD-related analogs, sulfonamide motifs, and other functionalized small-molecule scaffolds. Custom analog synthesis : substituent variation, linker-ready handles, and SAR-oriented intermediate preparation. Chiral and stereochemical review : chiral separation or asymmetric synthesis can be evaluated where relevant. Analytical support : HPLC, NMR, MS, and purity-method development according to project needs. Process development : route refinement and scale-up planning after technical review.
Overview
NRX-1933 (also known as 2-oxo-N-[3-(2H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)-1H-pyridine-3-carboxamide) (CAS 2763260-30-4, MF C14H9F3N6O2, MW 350.26) is a small-molecule scaffold studied in targeted protein degradation research, with potential relevance to molecular glue or E3-ligase modulation chemistry. Practical chemistry topics include enantioselective synthesis, scaffold modification, and related-substance profiling. Custom synthesis, process scale-up and supply planning are available through CHEMOS R&D and manufacturing facilities.
Applications
- NRX-1933 (2763260-30-4) as a starting point for downstream chemistry programs
- Custom synthesis of analog series for SAR exploration
- Process-development support for scalable scaffold preparation
- Reference research scaffold in degrader chemistry programs
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