1H-1,4-Benzodiazepine-7-carbonitrile derivative
1H-1,4-Benzodiazepine-7-carbonitrile derivative
Product summary
Quick view
- Product family
- PROTAC, E3 Ligands & Proximity-Inducing Building Blocks
- Chemical Name
- 1H-1,4-Benzodiazepine-7-carbonitrile derivative
CH57014 is listed by CHEMOS as 1H-1,4-Benzodiazepine-7-carbonitrile, 2,3,4,5-tetrahydro-1-[(1-methyl-1H-imidazol-5-yl)methyl]-3-(phenylmethyl)-4-(2-thienylsulfonyl)-, (3R)-, CAS 675125-62-9, with molecular weight 503.64.
No verified PubChem, PubMed, or NCI/CIR identity match is included, and the catalog record does not include formula or chemical name fields.
This catalog entry is limited to identity information. Structure, formula, and product-specific application details are not included.
Identity and specifications
| Catalog No. | CH57014 |
| CAS No. | 675125-62-9 |
| Product Name | 1H-1,4-Benzodiazepine-7-carbonitrile derivative |
| Molecular Weight | 503.64 (catalog value) |
| Molecular Formula | Not listed |
| Public CID | No public CID cited |
Additional material information
Characteristics
Detailed structure, formula, chemical name, and stereochemical assignment are not included in this catalog entry.
Related technical resources
PROTAC / TPD Building Blocks
CRBN and VHL ligand derivatives, ligand-linkers, bifunctional degrader intermediates, and linker-tuning building blocks.
PROTAC Linker Selection
Build linker series from both ligands, exit vectors, ternary-complex geometry, conformation, permeability, synthesis, and assay evidence.
Public references
- Catalytic in vivo protein knockdown by small-molecule PROTACs
Nature Chemical Biology, 2015
Product-family technical context
- Structural basis of PROTAC cooperative recognition for selective protein degradation
Nature Chemical Biology, 2017
Product-family technical context
- Structural Basis of PROTAC Cooperative Recognition for Selective Protein Degradation
Nature Chemical Biology, 2017
Product-family technical context
- Direct-to-Biology Accelerates PROTAC Synthesis and the Evaluation of Linker Effects on Permeability and Degradation
ACS Medicinal Chemistry Letters, 2022
Product-family technical context
Frequently Asked Questions
What is listed for CH57014?
CH57014 is listed with CAS 675125-62-9 and molecular weight 503.64.
What identity data is included?
The catalog entry includes the listed CAS and MW; PubChem, PubMed, and NCI/CIR checks did not verify the identity.
Why are application details omitted?
Identity and direct evidence were not verified, so molecular-glue and targeted-protein-degradation wording are not used.
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