2-((4-Acetylpiperazin-1-yl)methyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one
2-((4-Acetylpiperazin-1-yl)methyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one
Product summary
Quick view
- Product family
- PROTAC, E3 Ligands & Proximity-Inducing Building Blocks
- Chemical Name
- 2-((4-Acetylpiperazin-1-yl)methyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one
CH57016 is listed by CHEMOS as 2-((4-Acetylpiperazin-1-yl)methyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one, CAS 1333248-18-2, with molecular weight 406.48.
No verified PubChem, PubMed, or NCI/CIR identity match is included, and the catalog record does not include formula or chemical name fields.
This catalog entry is limited to identity information. Structure, formula, and product-specific application details are not included.
Identity and specifications
| Catalog No. | CH57016 |
| CAS No. | 1333248-18-2 |
| Product Name | 2-((4-Acetylpiperazin-1-yl)methyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one |
| Molecular Weight | 406.48 (catalog value) |
| Molecular Formula | Not listed |
| Public CID | No public CID cited |
Additional material information
Characteristics
Detailed structure, formula, chemical name, and stereochemical assignment are not included in this catalog entry.
Related technical resources
PROTAC / TPD Building Blocks
CRBN and VHL ligand derivatives, ligand-linkers, bifunctional degrader intermediates, and linker-tuning building blocks.
PROTAC Linker Selection
Build linker series from both ligands, exit vectors, ternary-complex geometry, conformation, permeability, synthesis, and assay evidence.
Public references
- Catalytic in vivo protein knockdown by small-molecule PROTACs
Nature Chemical Biology, 2015
Product-family technical context
- Structural basis of PROTAC cooperative recognition for selective protein degradation
Nature Chemical Biology, 2017
Product-family technical context
- Structural Basis of PROTAC Cooperative Recognition for Selective Protein Degradation
Nature Chemical Biology, 2017
Product-family technical context
- Direct-to-Biology Accelerates PROTAC Synthesis and the Evaluation of Linker Effects on Permeability and Degradation
ACS Medicinal Chemistry Letters, 2022
Product-family technical context
Frequently Asked Questions
What is listed for CH57016?
CH57016 is listed as 2-((4-Acetylpiperazin-1-yl)methyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one, CAS 1333248-18-2, with molecular weight 406.48.
What identity data is included?
The catalog entry includes the listed CAS and MW; PubChem, PubMed, and NCI/CIR checks did not verify the identity.
Why are application details omitted?
Identity and direct evidence were not verified, so molecular-glue, E3-ligase, and targeted-protein-degradation wording are not used.
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