IKZF2-degrader 2
IKZF2-degrader 2
Product summary
Quick view
- Product family
- PROTAC, E3 Ligands & Proximity-Inducing Building Blocks
- Chemical Name
- IKZF2-degrader 2
- MF
- C26H25ClFN5O3
- MW
- 509.96
IKZF2-degrader 2 is the product name for catalog CH57017.
This record matches CAS 2983841-00-3, molecular formula C26H25ClFN5O3, molecular weight about 510.0, PubChem CID 169206352, and InChIKey JRGGAIVXJQWLAP-UHFFFAOYSA-N.
The IUPAC name 3-[6-[5-chloro-1-methyl-4-(pyrrolidin-1-ylmethyl)pyrrolo[2,3-b]pyridin-6-yl]-7-fluoro-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione refers to the same compound identity.
Identity and specifications
| Catalog No. | CH57017 |
| CAS No. | 2983841-00-3 |
| Chemical Name | IKZF2-degrader 2 |
| IUPAC Name | 3-[6-[5-chloro-1-methyl-4-(pyrrolidin-1-ylmethyl)pyrrolo[2,3-b]pyridin-6-yl]-7-fluoro-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione |
| Molecular Formula | C26H25ClFN5O3 |
| Molecular Weight | 509.96 |
| PubChem CID | 169206352 |
| InChIKey | JRGGAIVXJQWLAP-UHFFFAOYSA-N |
Related technical resources
PROTAC / TPD Building Blocks
CRBN and VHL ligand derivatives, ligand-linkers, bifunctional degrader intermediates, and linker-tuning building blocks.
PROTAC Linker Selection
Build linker series from both ligands, exit vectors, ternary-complex geometry, conformation, permeability, synthesis, and assay evidence.
Public references
- IKZF2 degrader | PubChem CID 169206352
- Catalytic in vivo protein knockdown by small-molecule PROTACs
Nature Chemical Biology, 2015
Product-family technical context
- Structural basis of PROTAC cooperative recognition for selective protein degradation
Nature Chemical Biology, 2017
Product-family technical context
- Structural Basis of PROTAC Cooperative Recognition for Selective Protein Degradation
Nature Chemical Biology, 2017
Product-family technical context
- Direct-to-Biology Accelerates PROTAC Synthesis and the Evaluation of Linker Effects on Permeability and Degradation
ACS Medicinal Chemistry Letters, 2022
Product-family technical context
Frequently Asked Questions
What is IKZF2-degrader 2?
CH57017 is IKZF2-degrader 2, CAS 2983841-00-3, with molecular formula C26H25ClFN5O3, molecular weight about 510.0, and PubChem CID 169206352.
What is the InChIKey?
The InChIKey for this CAS record is JRGGAIVXJQWLAP-UHFFFAOYSA-N.
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