XMU-MP-8
XMU-MP-8
Product summary
Quick view
- Product family
- PROTAC, E3 Ligands & Proximity-Inducing Building Blocks
- Chemical Name
- XMU-MP-8
- MF
- C26H21F3N8S
- MW
- 534.6
XMU-MP-8 is a pyrazolopyrimidine thiourea compound identified by CAS 2271314-01-1.
The verified record matches molecular formula C26H21F3N8S, molecular weight about 534.6, PubChem CID 146621802, and InChIKey UPEIYMKISINCQK-UHFFFAOYSA-N.
The identifiers support comparison of the pyrazolopyrimidine, pyridinylmethylamino, thiourea, and trifluoromethyl phenyl features across catalog records.
Identity and specifications
| Catalog No. | CH57018 |
| CAS No. | 2271314-01-1 |
| Chemical Name | XMU-MP-8 |
| Molecular Formula | C26H21F3N8S |
| Molecular Weight | 534.6 |
| PubChem CID | 146621802 |
| IUPAC Name | 1-[3-[1-methyl-4-(pyridin-3-ylmethylamino)pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]-3-[3-(trifluoromethyl)phenyl]thiourea |
| Synonyms | A1JBJ |
| InChIKey | UPEIYMKISINCQK-UHFFFAOYSA-N |
Application context
- Chemical identity reference: supports matching XMU-MP-8 with CAS 2271314-01-1 and PubChem CID 146621802.
- Pyrazolopyrimidine thiourea context: provides a record for a pyridinylmethylamino pyrazolopyrimidine linked to a trifluoromethyl phenyl thiourea group.
- Catalog data alignment: helps keep formula C26H21F3N8S, molecular weight, CAS number, and InChIKey consistent across records.
Additional material information
Uses
XMU-MP-8 can be matched by CAS 2271314-01-1, formula C26H21F3N8S, molecular weight about 534.6, PubChem CID 146621802, and InChIKey UPEIYMKISINCQK-UHFFFAOYSA-N.
Characteristics
- Pyrazolo[3,4-d]pyrimidine thiourea structure with pyridinylmethylamino and trifluoromethyl phenyl groups.
- Fluorinated nitrogen- and sulfur-containing compound with formula C26H21F3N8S.
- CAS lookup resolves to PubChem CID 146621802, with A1JBJ listed as a synonym.
Related technical resources
PROTAC / TPD Building Blocks
CRBN and VHL ligand derivatives, ligand-linkers, bifunctional degrader intermediates, and linker-tuning building blocks.
PROTAC Linker Selection
Build linker series from both ligands, exit vectors, ternary-complex geometry, conformation, permeability, synthesis, and assay evidence.
Public references
- Xmu-MP-8 | PubChem CID 146621802
- Catalytic in vivo protein knockdown by small-molecule PROTACs
Nature Chemical Biology, 2015
Product-family technical context
- Structural basis of PROTAC cooperative recognition for selective protein degradation
Nature Chemical Biology, 2017
Product-family technical context
- Structural Basis of PROTAC Cooperative Recognition for Selective Protein Degradation
Nature Chemical Biology, 2017
Product-family technical context
- Direct-to-Biology Accelerates PROTAC Synthesis and the Evaluation of Linker Effects on Permeability and Degradation
ACS Medicinal Chemistry Letters, 2022
Product-family technical context
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