CHEMOS
XMU-MP-8

XMU-MP-8

Chemical Name

1-[3-[1-methyl-4-(pyridin-3-ylmethylamino)pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]-3-[3-(trifluoromethyl)phenyl]thiourea

XMU-MP-8•Molecular Glues
Structure: XMU-MP-8 structure, CAS 2271314-01-1, MW 534.56
Product No
CH57018
CAS
2271314-01-1
MF
C26H21F3N8S
MW
534.56
Specification
Catalog No.CH57018
CAS No.2271314-01-1
Molecular FormulaC26H21F3N8S
Molecular Weight534.56

CHEMOS Support for This Category

CHEMOS supports molecular glue and small-molecule degrader building-block chemistry, including analog preparation and route optimization. Scaffold preparation : IMiD-related analogs, sulfonamide motifs, and other functionalized small-molecule scaffolds. Custom analog synthesis : substituent variation, linker-ready handles, and SAR-oriented intermediate preparation. Chiral and stereochemical review : chiral separation or asymmetric synthesis can be evaluated where relevant. Analytical support : HPLC, NMR, MS, and purity-method development according to project needs. Process development : route refinement and scale-up planning after technical review.

Overview

XMU-MP-8 (also known as 1-[3-[1-methyl-4-(pyridin-3-ylmethylamino)pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]-3-[3-(trifluoromethyl)phenyl]thiourea) (CAS 2271314-01-1, MF C26H21F3N8S, MW 534.56) is a small-molecule scaffold studied in targeted protein degradation research, with potential relevance to molecular glue or E3-ligase modulation chemistry. Practical chemistry topics include enantioselective synthesis, scaffold modification, and related-substance profiling. Bench-scale to larger-scale production is supported through CHEMOS organic chemistry workflows and dedicated process-development resources.

Applications

  • XMU-MP-8 (2271314-01-1) supply and analog preparation for research programs
  • Process-development support for scalable scaffold preparation
  • Reference research scaffold in degrader chemistry programs
  • Molecular glue research scaffold for targeted protein degradation

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