2,2'-Dipyridyl disulfide
2-(pyridin-2-yldisulfanyl)pyridine
Product summary
Quick view
- Product family
- Click Chemistry & Bioconjugation Reagents
- Chemical Name
- 2-(pyridin-2-yldisulfanyl)pyridine
- MF
- C10H8N2S2
- MW
- 220.31
- Purity
- >=99.0% (GC)
2,2'-Dipyridyl disulfide is a pyridyl disulfide reagent for thiol-, sulfhydryl-, and disulfide-exchange chemistry. It is also known as 2,2'-dithiodipyridine, Aldrithiol-2, bis(2-pyridyl) disulfide, and 2PDS; the abbreviation 2,2'-DTDP is also used in the literature.
CH58001 is listed with CAS 2127-03-9, molecular formula C10H8N2S2, and molecular weight 220.31. It is used in R&D chemistry centered on pyridyl disulfide reactivity, sulfhydryl assay design, and disulfide-trapping studies.
Synonyms
2,2'-Dithiodipyridine; Aldrithiol-2; bis(2-pyridyl) disulfide; 2PDS; 2,2'-DTDP
Identity and specifications
| Catalog No. | CH58001 |
| CAS No. | 2127-03-9 |
| Molecular Formula | C10H8N2S2 |
| Molecular Weight | 220.31 |
| PubChem CID | 65093 |
| InChIKey | HAXFWIACAGNFHA-UHFFFAOYSA-N |
| Purity | >=99.0% (GC) |
Storage conditions
Room temperature; cool and dark place below 15 C; under inert gas
Technical attributes
- Reagent class
- Pyridyl disulfide reagent
- Reactive chemistry
- Thiol-disulfide exchange
- Research role
- Thiol and sulfhydryl assay reagent
- Grade
- for Peptide Synthesis (supplier designation)
- Packaging
- 5 g; 25 g; 250 g; Custom packaging on request
- Physical form
- Powder or crystalline powder
Application context
- Thiol and sulfhydryl assays: literature context involving 2,2'-DTDP / pyridyl disulfide chemistry for sulfhydryl-focused assay design.
- Disulfide-trapping work: relevant when disulfide exchange or thiol-reactive capture is part of the chemistry being studied.
- Pyridyl disulfide chemistry: a compact heterocyclic disulfide reagent in studies that reference 2PDS, Aldrithiol-2, or related naming.
Related technical resources
Public references
- A strain-promoted [3 + 2] azide-alkyne cycloaddition for covalent modification of biomolecules in living systems
Journal of the American Chemical Society, 2004
Product-family technical context
- Copper-free click chemistry for dynamic in vivo imaging
Proceedings of the National Academy of Sciences, 2007
Product-family technical context
- A Strain-Promoted [3 + 2] Azide–Alkyne Cycloaddition for Covalent Modification of Biomolecules in Living Systems
Journal of the American Chemical Society, 2004
Product-family technical context
- Tetrazine Ligation: Fast Bioconjugation Based on Inverse-Electron-Demand Diels–Alder Reactivity
Journal of the American Chemical Society, 2008
Product-family technical context
- PubChem Compound 65093
PubChem · CID 65093
Frequently Asked Questions
How is 2,2'-Dipyridyl disulfide used in R&D chemistry?
It is used in thiol and sulfhydryl assay chemistry, disulfide-trapping studies, and work that relies on pyridyl disulfide reactivity.
Similar Products
Need Help with Material Selection?
CHEMOS can review product fit, target structure, route questions, analytical expectations, and project-specific supply needs.