2'-Deoxyadenosine Monohydrate
(2R,3S,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol;hydrate
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- (2R,3S,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol;hydrate
- MF
- C10H15N5O4
- MW
- 269.26
- Purity
- 100%
2'-Deoxyadenosine monohydrate is the hydrated dAdo form of the purine DNA nucleoside, with adenine linked to 2-deoxy-β-D-ribose. CH64001 is identified by CAS 16373-93-6, molecular formula C10H15N5O4, molecular weight 269.26, and PubChem CID 9549172.
Keep this record separate from anhydrous 2'-deoxyadenosine, which is listed separately as CH64007. In research literature, 2'-deoxyadenosine appears as a deoxynucleoside-kinase substrate and as the natural dA reference in polymerase and nucleoside-chemistry studies.
Synonyms
2'-Deoxyadenosine monohydrate; dAdo monohydrate; 2'-deoxyriboadenosine hydrate
Identity and specifications
| Catalog No. | CH64001 |
| CAS No. | 16373-93-6 |
| Molecular Formula | C10H15N5O4 (monohydrate) |
| Molecular Weight | 269.26 (monohydrate) |
| PubChem CID | 9549172 |
| InChIKey | WZJWHIMNXWKNTO-VWZUFWLJSA-N |
| Purity | 100% |
Storage conditions
2-8 C
Technical attributes
- Nucleobase
- Adenine
- Sugar
- 2'-Deoxyribose
- Nucleoside class
- Purine 2'-deoxyribonucleoside
- Material form
- Monohydrate
- Packaging
- Custom packaging on request
- Water content
- 5-7.5%
- Physical form
- White to almost white crystal to powder
Application context
- Kinase phosphorylation research: literature reports 2'-deoxyadenosine as a substrate for deoxycytidine kinase and adenosine kinase.
- Polymerase building-block studies: modified dA building blocks are compared against the natural deoxyribonucleoside scaffold during polymerase-incorporation research.
- Nucleoside chemistry reference: the hydrated dAdo record provides a defined 2'-deoxyribonucleoside identity for DNA and oligonucleotide chemistry work.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 9549172
PubChem · CID 9549172
Frequently Asked Questions
Is CH64001 the monohydrate or anhydrous form?
It is the monohydrate (CAS 16373-93-6, C10H15N5O4, MW 269.26). The anhydrous 2'-deoxyadenosine (CAS 958-09-8) is listed as a separate CHEMOS product.
How is 2'-deoxyadenosine used as a kinase substrate?
It is phosphorylated by deoxycytidine kinase and adenosine kinase, so it is used as a defined purine deoxynucleoside substrate in kinase phosphorylation research.
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