2',3',5'-Tri-O-acetyl-D-adenosine
[(2R,3R,4R,5R)-3,4-diacetyloxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methyl acetate
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- [(2R,3R,4R,5R)-3,4-diacetyloxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methyl acetate
- MF
- C16H19N5O7
- MW
- 393.35
- Purity
- >=97%
2',3',5'-Tri-O-acetyl-D-adenosine is a protected adenosine derivative for nucleoside chemistry and adenosine-derivative synthesis research. It is also referenced as 2',3',5'-Tri-O-acetyladenosine, Tri-O-acetyladenosine, and adenosine 2',3',5'-triacetate.
CH58005 is listed with CAS 7387-57-7, molecular formula C16H19N5O7, and molecular weight 393.35. The compound fits literature and project records that involve protected adenosine derivatives, N6-substituted adenosine synthesis, or regioselective adenosine-derivative modification.
Synonyms
2',3',5'-Tri-O-acetyladenosine; Adenosine, 2',3',5'-triacetate; Tri-O-acetyladenosine; Adenosine 2',3',5'-triacetate
Identity and specifications
| Catalog No. | CH58005 |
| CAS No. | 7387-57-7 |
| Molecular Formula | C16H19N5O7 |
| Molecular Weight | 393.35 |
| PubChem CID | 96503 |
| InChIKey | GCVZNVTXNUTBFB-XNIJJKJLSA-N |
| Purity | >=97% |
Storage conditions
-20 C; protect from light
Technical attributes
- Nucleoside scaffold
- Adenosine
- Sugar protection
- 2',3',5'-tri-O-acetyl
- Material role
- Protected nucleoside derivative
- Packaging
- Custom packaging on request
- Physical form
- White to off-white powder
Application context
- Protected nucleoside synthesis: relevant to synthesis research built around protected adenosine and nucleoside derivatives.
- Adenosine-derivative modification: reported in workflows involving N6-substituted adenosines and regioselective modification of adenosine derivatives.
- Name reconciliation: helps match records that use Tri-O-acetyladenosine or adenosine 2',3',5'-triacetate naming.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 96503
PubChem · CID 96503
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