Advancing precision drug through innovative chemistry and advanced molecular technologies.
Integrated CDMO services spanning discovery, process development, custom synthesis and commercial manufacturing.
Delivering reliable CDMO solutions for innovative therapeutics worldwide.
Organische Synthese, Kundensynthese, Prozessentwicklung und Scale-up-Unterstützung für anspruchsvolle Chemieprojekte.
Synthese- und Analytiktechnologien für komplexe Moleküle.
CHEMOS ist ein synthesegetriebener CDMO mit Fokus auf organische Synthese, Kundensynthese, Routenentwicklung, Prozessentwicklung, Scale-up-Unterstützung und analytische Begleitung.
Nachrichten, Einblicke und Updates von CHEMOS.
FDA announced on July 16, 2026 that Lipfendra (enlicitide) was approved to be used with diet and exercise to reduce LDL-C in adults with high cholesterol or heterozygous familial hypercholesterolemia. FDA also states that Lipfendra is a tablet taken by mouth once daily and is the first oral therapy that blocks PCSK9.
Mehr lesenThe key correction is that the ACS Organic Process Research & Development paper describes LUNA18 (paluratide) through a liquid-phase peptide synthesis process, not a simple SPPS plus three-fragment route. The paper’s abstract says the authors departed from conventional solid-phase peptide synthesis and developed an LPPS process for an N-alkyl-rich cyclic undecapeptide KRAS inhibitor.
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The reported inclisiran architecture illustrates why an siRNA conjugate cannot be reduced to a sequence plus a targeting ligand. Descriptions of that architecture place a triantennary N-acetylgalactosamine (GalNAc) unit at the sense-strand terminus, combine 2'-fluoro and 2'-O-methyl ribose substitutions with terminal phosphorothioate linkages, and rely on the antisense strand for RNA-induced silencing complex (RISC) loading. Each element addresses a different constraint: cell uptake, nuclease exposure, strand handling, or intracellular recognition.
Von früher Routenbewertung bis Prozessentwicklung und Scale-up unterstützt CHEMOS Kundensynthese mit F&E-Erfahrung und Produktionsbasis.
