CHEMOS
Maleimide

Maleimide

Nombre químico

pyrrole-2,5-dione

Maleimide•ADC linker
Structure: Maleimide structure, CAS 541-59-3, MW 97.07
N.º de producto
CH53002
CAS
541-59-3
FM
C4H3NO2
PM
97.07
Especificación
Catalog No.CH53002
CAS No.541-59-3
Molecular FormulaC4H3NO2
Molecular Weight97.07

CHEMOS Support for This Category

CHEMOS supports ADC linker and bioconjugation building-block projects from route design through custom synthesis and process optimization. Custom linker synthesis : peptide, PEG, self-immolative, cleavable, and non-cleavable linker structures. Functional-handle installation : NHS ester, maleimide, azide, alkyne, and other conjugation-ready groups. Multi-step route development : protecting-group strategy, coupling optimization, purification review, and impurity-profile control. Analytical support : HPLC, NMR, MS, and chiral methods where applicable. Scale-up planning : laboratory-to-production transfer can be evaluated after route feasibility and specification review.

Descripción general

Maleimide (also known as pyrrole-2,5-dione) (CAS 541-59-3, MF C4H3NO2, MW 97.07) is an antibody-drug conjugate (ADC) linker or bioconjugation building block. Chemistry topics around such compounds typically cover the reactive handle (maleimide / NHS / DBCO / azide), linker stability in plasma, and release behaviour intracellularly. CHEMOS process-development team and large production base can support route refinement, scale-up and custom synthesis on request.

Aplicaciones

  • Maleimide (CAS 541-59-3) preparation, route refinement, and analytical-control planning
  • Click-chemistry coupling (DBCO / azide) for bioconjugation programs
  • Custom linker / payload-linker synthesis on request
  • Process-development support for scalable linker preparation

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