Tasisulam

Tasisulam

Nombre químico

N-(5-bromothiophen-2-yl)sulfonyl-2,4-dichlorobenzamide

TasisulamMolecular Glues
Structure: Tasisulam structure, CAS 519055-62-0, MW 415.11
N.º de producto
CH57003
CAS
519055-62-0
FM
C11H6BrCl2NO3S2
PM
415.11
Especificación
Catalog No.CH57003
CAS No.519055-62-0
Molecular FormulaC11H6BrCl2NO3S2
Molecular Weight415.11

CHEMOS Support for This Category

CHEMOS supports molecular glue and small-molecule degrader building-block chemistry, including analog preparation and route optimization. Scaffold preparation : IMiD-related analogs, sulfonamide motifs, and other functionalized small-molecule scaffolds. Custom analog synthesis : substituent variation, linker-ready handles, and SAR-oriented intermediate preparation. Chiral and stereochemical review : chiral separation or asymmetric synthesis can be evaluated where relevant. Analytical support : HPLC, NMR, MS, and purity-method development according to project needs. Process development : route refinement and scale-up planning after technical review.

Descripción general

Tasisulam (also known as N-(5-bromothiophen-2-yl)sulfonyl-2,4-dichlorobenzamide) (CAS 519055-62-0, MF C11H6BrCl2NO3S2, MW 415.11) is a small-molecule scaffold studied in targeted protein degradation research, with potential relevance to molecular glue or E3-ligase modulation chemistry. Practical chemistry topics include enantioselective synthesis, scaffold modification, and related-substance profiling. Bench-scale to larger-scale production is supported through CHEMOS organic chemistry workflows and dedicated process-development resources.

Aplicaciones

  • Tasisulam (519055-62-0) as a starting point for downstream chemistry programs
  • Molecular glue research scaffold for targeted protein degradation
  • Custom synthesis of analog series for SAR exploration
  • Reference research scaffold in degrader chemistry programs

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