Guanosine
2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
Resumen del producto
Vista rápida
- Familia de productos
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Nombre químico
- 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
- FM
- C10H13N5O5
- PM
- 283.24
- Pureza
- >98.0% (HPLC, titration)
Guanosine is the canonical purine RNA nucleoside, with guanine linked to β-D-ribose. CH64011 is identified by CAS 118-00-3, molecular formula C10H13N5O5, molecular weight 283.24, and PubChem CID 135398635. The corresponding 2'-deoxyguanosine records are cataloged separately.
The supported research context is PNP enzymology and RNA nucleoside chemistry: guanosine is a purine nucleoside phosphorylase substrate and an unmodified purine ribonucleoside reference.
Sinónimos
Guanosine; guanine riboside; Guo
Identidad y especificaciones
| Catalog No. | CH64011 |
| CAS No. | 118-00-3 |
| Molecular Formula | C10H13N5O5 |
| Molecular Weight | 283.24 |
| PubChem CID | 135398635 |
| InChIKey | NYHBQMYGNKIUIF-UUOKFMHZSA-N |
| Purity | >98.0% (HPLC, titration) |
Condiciones de almacenamiento
Room temperature; cool and dark place below 15 C
Atributos técnicos
- Nucleobase
- Guanine
- Sugar
- D-Ribose
- Nucleoside class
- Purine ribonucleoside
- Packaging
- 5 g; 25 g; 100 g; Custom packaging on request
- Physical form
- Solid; white to almost white powder to crystal
Contexto de aplicación
- Purine nucleoside phosphorylase substrate: guanosine is used as a defined substrate in PNP enzymology research.
- Purine RNA nucleoside reference: CH64011 provides the unmodified guanosine identity for RNA and nucleoside chemistry comparisons.
Recursos técnicos relacionados
Fuentes públicas
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- Compuesto de PubChem 135398635
PubChem · CID 135398635
Preguntas frecuentes
Is CH64011 the RNA or DNA nucleoside?
It is guanosine, the RNA (ribo) nucleoside. The DNA counterpart, 2'-deoxyguanosine, is listed separately by CHEMOS.
How is guanosine used in enzyme research?
Guanosine is a substrate of purine nucleoside phosphorylase (PNP), which phosphorolyzes purine ribonucleosides, so it is used as a reference substrate in PNP enzymology.
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