2'-Fluoro-2'-deoxyguanosine
Oligonucleotide Synthesis, RNA Raw Materials & Modification
Resumen del producto
Vista rápida
- Familia de productos
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- FM
- C10H12FN5O4
- PM
- 285.23
- Pureza
- >=98% (HPLC)
2'-Fluoro-2'-deoxyguanosine (2'-F-dG) is a guanosine analog in which the 2'-hydroxyl of the sugar is replaced by fluorine. CH64027 is identified by CAS 78842-13-4, molecular formula C10H12FN5O4, molecular weight 285.23, and PubChem CID 135415565.
The cited oligonucleotide literature discusses 2'-fluoro modifications in siRNA and antisense research for nuclease resistance and binding affinity. CH64027 provides the guanosine 2'-fluoro-2'-deoxy nucleoside identity for related oligonucleotide-modification studies.
Sinónimos
2'-Fluoro-2'-deoxyguanosine; 2'-F-dG; 2'-F-G
Identidad y especificaciones
| Catalog No. | CH64027 |
| CAS No. | 78842-13-4 |
| Molecular Formula | C10H12FN5O4 |
| Molecular Weight | 285.23 |
| PubChem CID | 135415565 |
| InChIKey | UXUZARPLRQRNNX-DXTOWSMRSA-N |
| Purity | >=98% (HPLC) |
Condiciones de almacenamiento
0-10 C
Atributos técnicos
- Nucleobase
- Guanine
- Sugar modification
- 2'-Fluoro-2'-deoxy
- Nucleoside class
- 2'-Fluoro purine nucleoside
- Packaging
- 1 g; 2 g; 5 g; 10 g; 200 mg and 1 g glass bottles with plastic inserts; Custom packaging on request
- Physical form
- Solid; white to light yellow powder to crystal
Contexto de aplicación
- 2'-F oligonucleotide research: CH64027 is relevant to siRNA and antisense modification studies involving 2'-fluoro guanosine residues.
- Modified-nucleic-acid studies: the 2'-fluoro motif is discussed in duplex-affinity and nuclease-resistance research on modified oligonucleotides.
- 2'-F nucleoside reference: CH64027 provides the 2'-fluoro-2'-deoxyguanosine identity for nucleoside chemistry research.
Recursos técnicos relacionados
Fuentes públicas
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- Compuesto de PubChem 135415565
PubChem · CID 135415565
Preguntas frecuentes
How is 2'-F-dG different from 2'-deoxyguanosine?
2'-Deoxyguanosine has a hydrogen at the 2' position; 2'-fluoro-2'-deoxyguanosine has a fluorine there. 2'-deoxyguanosine is cataloged separately.
Productos similares
¿Necesita ayuda para seleccionar materiales?
CHEMOS puede revisar adecuación del producto, estructura objetivo, preguntas de ruta, expectativas analíticas y necesidades de suministro del proyecto.