Lipig
Oligonucleotide Conjugation & Delivery Ligands
Resumen del producto
Vista rápida
- Familia de productos
- Oligonucleotide Conjugation & Delivery Ligands
- FM
- C78H125N7O42
- PM
- 1832.8
- Pureza
- >98%
Lipig is a PubChem-verified acetyl-protected N-acetyl-sugar glycoconjugate building block catalogued in the CHEMOS GalNAc/conjugate line. Key identifiers include CAS 1332358-27-6, molecular formula C78H125N7O42, molecular weight 1832.8, InChIKey RNUIVLALNYHRTI-OIZVDVEISA-N, and PubChem CID 58409185.
Lipig is presented for oligonucleotide conjugation / GalNAc-type delivery-ligand building-block context. GalNAc-ASGPR binding is included only as molecular-recognition background for the ligand class, while CH67006 remains a catalog building-block identity.
Sinónimos
Lipig; acetyl-protected N-acetyl-sugar glycoconjugate; GalNAc-type glycoconjugate building block
Identidad y especificaciones
| Catalog No. | CH67006 |
| CAS No. | 1332358-27-6 |
| Molecular Formula | C78H125N7O42 |
| Molecular Weight | 1832.8 |
| PubChem CID | 58409185 |
| InChIKey | RNUIVLALNYHRTI-OIZVDVEISA-N |
| Purity | >98% |
Condiciones de almacenamiento
-20 +/- 5 C
Atributos técnicos
- Material class
- Acetyl-protected N-acetyl-sugar glycoconjugate
- Structural family
- GalNAc-type glycoconjugate
- Protection state
- Acetyl-protected
- Packaging
- Custom packaging on request
Contexto de aplicación
- Glycoconjugate building block: a PubChem-verified acetyl-protected N-acetyl-sugar conjugate for oligonucleotide conjugation / GalNAc-type delivery-ligand chemistry.
- Building-block scope: use the record for identity matching and conjugation-context inquiries for the listed building block.
- GalNAc class context: GalNAc ligands bind the asialoglycoprotein receptor (ASGPR), cited here only as molecular-recognition background.
Recursos técnicos relacionados
administración dirigida a hepatocitos
ligandos GalNAc, grupos reactivos de conjugación de oligos, conjugados lipídicos y enlazadores para administración dirigida al hígado.
GalNAc vs conjugación lipídica
Comparar GalNAc multivalente dirigido a receptor y conjugación lipídica dependiente de estructura como estrategias distintas.
Fuentes públicas
- Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency in mice
Nucleic Acids Research, 2014
Product-family technical context
- Multivalent N-acetylgalactosamine-conjugated siRNA localizes in hepatocytes and elicits RNAi-mediated gene silencing
Journal of the American Chemical Society, 2014
Product-family technical context
- siRNA Conjugates Carrying Sequentially Assembled Trivalent N-Acetylgalactosamine Linked Through Nucleosides Elicit Robust Gene Silencing In Vivo in Hepatocytes
ACS Chemical Biology, 2015
Product-family technical context
- Comparative Characterization of Hepatic Distribution and mRNA Reduction of Antisense Oligonucleotides Conjugated with Triantennary N-Acetyl Galactosamine and Lipophilic Ligands
Journal of Pharmacology and Experimental Therapeutics, 2016
Product-family technical context
- Compuesto de PubChem 58409185
PubChem · CID 58409185
Preguntas frecuentes
What is Lipig?
It is a PubChem-verified acetyl-protected N-acetyl-sugar glycoconjugate building block (CAS 1332358-27-6, C78H125N7O42) catalogued in the CHEMOS GalNAc/conjugate line.
How should the GalNAc-ASGPR context be read?
GalNAc-ASGPR binding is molecular-recognition background for the ligand class. CH67006 is presented here as a catalog building-block identity.
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