NOTA-bis(tBu)ester

NOTA-bis(tBu)ester

化学名

2-[4,7-bis[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,4,7-triazonan-1-yl]acetic acid

NOTA-bis(tBu)esterNOTA
Structure: NOTA-bis(tBu)ester structure, CAS 1161415-28-6, MW 415.52
製品番号
CH55005
CAS
1161415-28-6
分子式
C20H37N3O6
分子量
415.52
仕様
Catalog No.CH55005
CAS No.1161415-28-6
Molecular FormulaC20H37N3O6
Molecular Weight415.52

CHEMOS Support for This Category

CHEMOS supports NOTA, NODAGA, and related chelator building-block projects for research and development use. NOTA-family derivatives : protected, activated, and pre-conjugated variants for downstream chemistry. Custom conjugate intermediates : chelator-linker and chelator-linker-peptide building blocks. Trace-metal awareness : process and analytical planning for radiolabeling-sensitive intermediates. Moisture-sensitive handling : packaging and handling requirements can be reviewed by compound form. Technical documentation : batch-specific COA and supporting technical information are provided according to confirmed specification.

概要

NOTA-bis(tBu)ester (also known as 2-[4,7-bis[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,4,7-triazonan-1-yl]acetic acid) (CAS 1161415-28-6, MF C20H37N3O6, MW 415.52) is part of the NOTA / NODAGA chelator class used in PET tracer development. Programs working with this compound typically focus on selective ring functionalisation, residual metal control, and conjugate compatibility with biomolecules. Bench-scale to larger-scale production is supported through CHEMOS organic chemistry workflows and dedicated process-development resources.

アプリケーション

  • NOTA-bis(tBu)ester (1161415-28-6) as a starting point for downstream chemistry programs
  • Trace-metal control studies for PET tracer chemistry
  • PET tracer chemistry — ⁶⁸Ga and ⁶⁴Cu radiopharmaceutical building block
  • Rapid radiometal complexation studies for short-half-life isotopes

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