Propargyl-NOTA(tBu)2
化学名
tert-butyl 2-[4-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-7-[2-oxo-2-(prop-2-ynylamino)ethyl]-1,4,7-triazonan-1-yl]acetate
Propargyl-NOTA(tBu)2•NOTA
Structure: 
製品番号
CH55019
CAS
1924677-40-6
分子式
C23H40N4O5
分子量
452.59
仕様
| Catalog No. | CH55019 |
| CAS No. | 1924677-40-6 |
| Molecular Formula | C23H40N4O5 |
| Molecular Weight | 452.59 |
CHEMOS Support for This Category
CHEMOS supports NOTA, NODAGA, and related chelator building-block projects for research and development use. NOTA-family derivatives : protected, activated, and pre-conjugated variants for downstream chemistry. Custom conjugate intermediates : chelator-linker and chelator-linker-peptide building blocks. Trace-metal awareness : process and analytical planning for radiolabeling-sensitive intermediates. Moisture-sensitive handling : packaging and handling requirements can be reviewed by compound form. Technical documentation : batch-specific COA and supporting technical information are provided according to confirmed specification.
概要
Propargyl-NOTA(tBu)2 (also known as tert-butyl 2-[4-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-7-[2-oxo-2-(prop-2-ynylamino)ethyl]-1,4,7-triazonan-1-yl]acetate) (CAS 1924677-40-6, MF C23H40N4O5, MW 452.59) belongs to the NOTA / NODAGA macrocyclic chelator family used in radiopharmaceutical research. Typical chemistry questions involve protection-group strategy, mono-functionalisation, and conjugation chemistry for peptide or antibody coupling. CHEMOS process-development team and large production base can support route refinement, scale-up and custom synthesis on request.
アプリケーション
- Propargyl-NOTA(tBu)2 (1924677-40-6) as a starting point for downstream chemistry programs
- Rapid radiometal complexation studies for short-half-life isotopes
- Custom synthesis of mono-functionalised NOTA / NODAGA derivatives
- Trace-metal control studies for PET tracer chemistry