CHEMOS
β-Sitosterol

β-Sitosterol

Chemical Name

(3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

β-Sitosterol•LNP
Structure: β-Sitosterol structure, CAS 83-46-5, MW 414.72
Product No
CH51001
CAS
83-46-5
MF
C29H50O
MW
414.72
Specification
Catalog No.CH51001
CAS No.83-46-5
Molecular FormulaC29H50O
Molecular Weight414.72

CHEMOS Support for This Category

CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.

Overview

β-Sitosterol (also known as (3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol) (CAS 83-46-5, MF C29H50O, MW 414.72) is used as an auxiliary lipid / sterol component in liposomal and LNP formulation research, often supporting bilayer stability or curvature control. Programs working with this material usually review identity, stereochemistry, and related sterol or surfactant species. CHEMOS process chemistry, organic synthesis routes and project scale-up support are offered for downstream programs.

Applications

  • β-Sitosterol (CAS 83-46-5) preparation, route refinement, and analytical-control planning
  • Sterol / surfactant supply for bilayer-property and curvature studies
  • Process-development support for scalable auxiliary-lipid preparation
  • Auxiliary lipid component in liposomal and LNP formulation research

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