CHEMOS
DC-CHOL

DC-CHOL

Chemical Name

[(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] N-[2-(dimethylamino)ethyl]carbamate;hydrochloride

DC-CHOL•LNP
Structure: DC-CHOL structure, CAS 166023-21-8, MW 537.26
Product No
CH51024
CAS
166023-21-8
MF
C32H57ClN2O2
MW
537.26
Specification
Catalog No.CH51024
CAS No.166023-21-8
Molecular FormulaC32H57ClN2O2
Molecular Weight537.26

CHEMOS Support for This Category

CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.

Overview

DC-CHOL (also known as [(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] N-[2-(dimethylamino)ethyl]carbamate;hydrochloride) (CAS 166023-21-8, MF C32H57ClN2O2, MW 537.26) is a sterol- or surfactant-class lipid component used in delivery system research. Practical chemistry topics include stereo-purity, related sterols / fatty-acid derivatives, and behaviour in lipid bilayers. Bench-scale to larger-scale production is supported through CHEMOS organic chemistry workflows and dedicated process-development resources.

Applications

  • DC-CHOL (CAS 166023-21-8) preparation, route refinement, and analytical-control planning
  • Process-development support for scalable auxiliary-lipid preparation
  • Auxiliary lipid component in liposomal and LNP formulation research
  • Custom synthesis of related sterol or surfactant analogs

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