CHEMOS
DEPC

DEPC

Chemical Name

[(2R)-2,3-bis[[(Z)-docos-13-enoyl]oxy]propyl] 2-(trimethylazaniumyl)ethyl phosphate

DEPC•LNP
Structure: DEPC structure, CAS 51779-95-4, MW 898.33
Product No
CH51029
CAS
51779-95-4
MF
C52H100NO8P
MW
898.33
Specification
Catalog No.CH51029
CAS No.51779-95-4
Molecular FormulaC52H100NO8P
Molecular Weight898.33

CHEMOS Support for This Category

CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.

Overview

DEPC (also known as [(2R)-2,3-bis[[(Z)-docos-13-enoyl]oxy]propyl] 2-(trimethylazaniumyl)ethyl phosphate) (CAS 51779-95-4, MF C52H100NO8P, MW 898.33) is a helper-lipid phospholipid component of relevance to liposome and LNP research. Programs working with this lipid focus on chain-length specificity, oxidation control for unsaturated tails, and analytical separation of related species. Bench-scale to larger-scale production is supported through CHEMOS organic chemistry workflows and dedicated process-development resources.

Applications

  • DEPC (CAS 51779-95-4) route review and custom analog preparation
  • Process-development support for scalable phospholipid preparation
  • Reference material in liposome composition optimisation studies
  • Helper phospholipid component in LNP and liposomal formulation research

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