DOTMA
DOTMA
Product summary
Quick view
- Product family
- LNP & Nucleic Acid Delivery Lipids
- Chemical Name
- DOTMA
- MF
- C42H84ClNO2
- MW
- 670.59
DOTMA is a quaternary ammonium cationic lipid identified by CAS 104872-42-6.
PubChem CID 6438350 and ChemicalBook both support the formula C42H84ClNO2 and molecular weight about 670.6 for the DOTMA chloride identity.
The product page uses DOTMA / DOTMA chloride naming and keeps application language to cationic liposome and lipid-system research.
Identity and specifications
| Catalog No. | CH51032 |
| CAS No. | 104872-42-6 |
| Chemical Name | DOTMA |
| Synonyms | DOTMA chloride; N-[1-(2,3-Dioleyloxy)propyl]-N,N,N-trimethylammonium chloride; 1,2-di-O-octadecenyl-3-trimethylammonium propane chloride salt |
| Molecular Formula | C42H84ClNO2 |
| Molecular Weight | 670.59 |
| PubChem CID | 6438350 |
| InChIKey | LDGWQMRUWMSZIU-LQDDAWAPSA-M |
Application context
- Cationic lipid identity work: supports matching DOTMA, DOTMA chloride, and N-[1-(2,3-Dioleyloxy)propyl]-N,N,N-trimethylammonium chloride naming to CAS 104872-42-6.
- Cationic liposome research: DOTMA is represented in literature on cationic liposome composition and membrane interaction studies.
- DOTMA-containing lipid-system studies: DOTMA appears in research comparing lipid components and lipid-system behavior.
Additional material information
Uses
DOTMA can be matched by CAS 104872-42-6, PubChem CID 6438350, formula C42H84ClNO2, and InChIKey LDGWQMRUWMSZIU-LQDDAWAPSA-M. The product page is focused on DOTMA chloride identity, cationic lipid context, and lipid-system research background.
Characteristics
- Quaternary ammonium cationic lipid commonly indexed under DOTMA chloride naming.
- Formula C42H84ClNO2 and molecular weight 670.59 in the catalog record.
- PubChem uses `(Z)-octadec-9-enoxy` chain wording, so stereochemical naming is kept aligned with verified records.
Related technical resources
Public references
- 1,2-di-O-octadecenyl-3-trimethylammonium propane (chloride salt) | PubChem CID 16730297
- High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing
PNAS, 2018
Product-family technical context
- Selective organ targeting nanoparticles for tissue-specific mRNA delivery and CRISPR-Cas gene editing
Nature Nanotechnology, 2020
Product-family technical context
- Rational Design of Cationic Lipids for siRNA Delivery
Nature Biotechnology, 2010
Product-family technical context
- Biodegradable Lipids Enabling Rapidly Eliminated Lipid Nanoparticles for Systemic Delivery of RNAi Therapeutics
Molecular Therapy, 2013
Product-family technical context
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