CHEMOS
DPPS

DPPS

Chemical Name

1,2-Dipalmitoyl-sn-glycero-3-phospho-L-serine sodium salt

DPPS•LNP
Structure: DPPS structure, CAS 145849-32-7, MW 757.96
Product No
CH51033
CAS
145849-32-7
MF
C38H73NNaO10P
MW
757.96
Specification
Catalog No.CH51033
CAS No.145849-32-7
Molecular FormulaC38H73NNaO10P
Molecular Weight757.96

CHEMOS Support for This Category

CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.

Overview

DPPS (also known as 1,2-Dipalmitoyl-sn-glycero-3-phospho-L-serine sodium salt) (CAS 145849-32-7, MF C38H73NNaO10P, MW 757.96) belongs to the helper phospholipid class used in nucleic acid delivery system research and liposomal drug carriers. Typical chemistry topics include stereo-purity at the glycerol backbone, residual free fatty acid, and related diacyl regio-isomers. CHEMOS process-development team and large production base can support route refinement, scale-up and custom synthesis on request.

Applications

  • DPPS (145849-32-7) as a starting point for downstream chemistry programs
  • Helper phospholipid component in LNP and liposomal formulation research
  • Bilayer-property studies in nucleic-acid delivery system development
  • Pulmonary surfactant and biophysical research applications

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