CHEMOS
1-Oleoyl-sn-glycero-3-phosphocholine

1-Oleoyl-sn-glycero-3-phosphocholine

Chemical Name

[(2R)-2-hydroxy-3-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate

1-Oleoyl-sn-glycero-3-phosphocholine•LNP
Structure: 1-Oleoyl-sn-glycero-3-phosphocholine structure, CAS 19420-56-5, MW 521.67
Product No
CH51035
CAS
19420-56-5
MF
C26H52NO7P
MW
521.67
Specification
Catalog No.CH51035
CAS No.19420-56-5
Molecular FormulaC26H52NO7P
Molecular Weight521.67

CHEMOS Support for This Category

CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.

Overview

1-Oleoyl-sn-glycero-3-phosphocholine (also known as [(2R)-2-hydroxy-3-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate) (CAS 19420-56-5, MF C26H52NO7P, MW 521.67) is a helper-lipid phospholipid component of relevance to liposome and LNP research. Programs working with this lipid focus on chain-length specificity, oxidation control for unsaturated tails, and analytical separation of related species. Custom synthesis, process scale-up and supply planning are available through CHEMOS R&D and manufacturing facilities.

Applications

  • 1-Oleoyl-sn-glycero-3-phosphocholine (CAS 19420-56-5) route review and custom analog preparation
  • Pulmonary surfactant and biophysical research applications
  • Custom synthesis of acyl-chain or head-group variants
  • Process-development support for scalable phospholipid preparation

Need Custom Synthesis?

Our CDMO team provides end-to-end custom synthesis support from discovery through process development and scale-up.

Explore CDMO Services