CHEMOS
DAPC; 1,2-Diarachidoyl-sn-glycero-3-phosphocholine

DAPC; 1,2-Diarachidoyl-sn-glycero-3-phosphocholine

Chemical Name

[(2R)-2,3-di(icosanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate

DAPC; 1,2-Diarachidoyl-sn-glycero-3-phosphocholine•LNP
Structure: DAPC; 1,2-Diarachidoyl-sn-glycero-3-phosphocholine structure, CAS 61596-53-0, MW 846.25
Product No
CH51057
CAS
61596-53-0
MF
C48H96NO8P
MW
846.25
Specification
Catalog No.CH51057
CAS No.61596-53-0
Molecular FormulaC48H96NO8P
Molecular Weight846.25

CHEMOS Support for This Category

CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.

Overview

DAPC; 1,2-Diarachidoyl-sn-glycero-3-phosphocholine (also known as [(2R)-2,3-di(icosanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate) (CAS 61596-53-0, MF C48H96NO8P, MW 846.25) is a helper-lipid phospholipid component of relevance to liposome and LNP research. Programs working with this lipid focus on chain-length specificity, oxidation control for unsaturated tails, and analytical separation of related species. Custom synthesis, process scale-up and supply planning are available through CHEMOS R&D and manufacturing facilities.

Applications

  • DAPC; 1,2-Diarachidoyl-sn-glycero-3-phosphocholine (61596-53-0) as a starting point for downstream chemistry programs
  • Bilayer-property studies in nucleic-acid delivery system development
  • Pulmonary surfactant and biophysical research applications
  • Custom synthesis of acyl-chain or head-group variants

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